Dawn C Newcomb
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Explore the profile of Dawn C Newcomb including associated specialties, affiliations and a list of published articles.
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90
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3525
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Recent Articles
1.
Stier M, Sewell A, Mwizerwa E, Sim C, Tanner S, Nichols C, et al.
bioRxiv
. 2025 Feb;
PMID: 39975258
Host immunity in sepsis has features of hyperinflammation together with progressive immunosuppression, particularly among CD4 T cells, that can predispose to secondary infections and ineffectual organ recovery. Metabolic and immunologic...
2.
Lubner R, Dorismond C, Krysinski M, Li P, Chandra R, Turner J, et al.
Int Forum Allergy Rhinol
. 2024 Dec;
15(3):350-353.
PMID: 39624918
CRS patients with asthma show differential nasal mucus cytokine signatures based on endotype. IL-7 concentration is positively associated with higher %FEV1 and %FVC in CRS patients with asthma.
3.
Toki S, Abney M, Zhang J, Rusznak M, Warren C, Newcomb D, et al.
Allergy
. 2024 Nov;
79(12):3373-3384.
PMID: 39559998
Background: Anti-inflammatory effects of incretin signaling through the glucagon-like peptide-1 receptor (GLP-1R) and the glucose-dependent insulinotropic polypeptide receptor (GIPR) in mice have been reported. Therefore, we hypothesized that signaling through...
4.
Chowdhury N, Cephus J, Henriquez Pilier E, Wolf M, Madden M, Kuehnle S, et al.
J Clin Invest
. 2024 Oct;
134(23).
PMID: 39404231
Female individuals have an increased prevalence of many Th17 cell-mediated diseases, including asthma. Androgen signaling decreases Th17 cell-mediated airway inflammation, and Th17 cells rely on glutaminolysis. However, it remains unclear...
5.
Subset-specific mitochondrial stress and DNA damage shape T cell responses to fever and inflammation
Heintzman D, Sinard R, Fisher E, Ye X, Patterson A, Elasy J, et al.
Sci Immunol
. 2024 Sep;
9(99):eadp3475.
PMID: 39303018
Heat is a cardinal feature of inflammation, yet its impacts on immune cells remain uncertain. We show that moderate-grade fever temperatures (39°C) increased murine CD4 T cell metabolism, proliferation, and...
6.
Berdnikovs S, Newcomb D, Hartert T
Front Pediatr
. 2024 Aug;
12:1441293.
PMID: 39156016
Childhood asthma is a common chronic disease of the airways that results from host and environment interactions. Most risk factor studies of asthma point to the first year of life...
7.
Berdnikovs S, Newcomb D, McKernan K, Kuehnle S, Haruna N, Gebretsadik T, et al.
bioRxiv
. 2024 Jul;
PMID: 39026695
Summary: Nasal airway epithelial cells from children with wheeze are characterized by altered development and increased susceptibility to RSV infection.
8.
Gutor S, Salinas R, Nichols D, Bazzano J, Han W, Gokey J, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 Feb;
326(5):L539-L550.
PMID: 38410870
Soldiers deployed to Iraq and Afghanistan have a higher prevalence of respiratory symptoms than nondeployed military personnel and some have been shown to have a constellation of findings on lung...
9.
Foer D, Amin T, Nagai J, Tani Y, Feng C, Liu T, et al.
J Immunol
. 2023 Oct;
211(12):1806-1813.
PMID: 37870292
Platelets are key contributors to allergic asthma and aspirin-exacerbated respiratory disease (AERD), an asthma phenotype involving platelet activation and IL-33-dependent mast cell activation. Human platelets express the glucagon-like peptide-1 receptor...
10.
Norlander A, Abney M, Cephus J, Roe C, Irish J, Shelburne N, et al.
Am J Respir Crit Care Med
. 2023 Sep;
208(11):1249-1250.
PMID: 37774400
No abstract available.