David Weigt
Overview
Explore the profile of David Weigt including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
31
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Recent Articles
1.
Unger M, Schumacher L, Enzlein T, Weigt D, Zamek-Gliszczynski M, Schwab M, et al.
Anal Chem
. 2020 Sep;
92(17):11851-11859.
PMID: 32867487
OATP2B1, a member of the solute carrier (SLC) transporter family, is an important mechanism of substrate drug uptake in the intestine and liver and therefore a determinant of clinical pharmacokinetics...
2.
Weigt D, Parrish C, Krueger J, Oleykowski C, Rendina A, Hopf C
Cell Chem Biol
. 2019 Jul;
26(9):1322-1331.e4.
PMID: 31279605
Human cancers require fatty acid synthase (FASN)-dependent de novo long-chain fatty acid synthesis for proliferation. FASN is therefore an attractive drug target, but fast technologies for reliable label-free cellular compound...
3.
Weigt D, Sammour D, Ulrich T, Munteanu B, Hopf C
Sci Rep
. 2018 Jul;
8(1):11260.
PMID: 30050068
Recent advances in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry have enabled whole cell-MALDI mass spectrometry biotyping of drug-treated cultured cells for rapid monitoring of known abundant pharmacodynamic protein markers such...
4.
Weigt D, Hopf C, Medard G
Clin Epigenetics
. 2016 Jul;
8:76.
PMID: 27437033
Some epigenetic modifier proteins have become validated clinical targets. With a few small molecule inhibitors already approved by national health administrations and many more in the pharmaceutical industry pipelines, there...
5.
Jacquez P, Lei N, Weigt D, Xiao C, Sun J
Protein Expr Purif
. 2014 Jan;
95:149-55.
PMID: 24380801
The ectodomain of anthrax toxin receptor 2 (ANTXR2) is composed of a von Willebrand factor A (VWA) domain that binds to anthrax toxin protective antigen (PA) and a newly defined...