David W Wegman
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Explore the profile of David W Wegman including associated specialties, affiliations and a list of published articles.
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10
Citations
49
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Recent Articles
1.
Hu L, Stasheuski A, Wegman D, Wu N, Yang B, Hayder H, et al.
Anal Chem
. 2017 Mar;
89(8):4743-4748.
PMID: 28339187
Accurate quantitation of microRNA (miRNA) in tissue samples is required for validation and clinical use of miRNA-based disease biomarkers. Since sample processing, such as RNA extraction, introduces undesirable biases, it...
2.
Wegman D, Ghasemi F, Stasheuski A, Khorshidi A, Yang B, Liu S, et al.
Anal Chem
. 2016 Jan;
88(4):2472-7.
PMID: 26756139
Direct quantitative analysis of multiple miRNAs (DQAMmiR) utilizes CE with fluorescence detection for fast, accurate, and sensitive quantitation of multiple miRNAs. Here we report on achieving single-nucleotide specificity and, thus,...
3.
Wegman D, Ghasemi F, Khorshidi A, Yang B, Liu S, Yousef G, et al.
Anal Chem
. 2014 Dec;
87(2):1404-10.
PMID: 25495883
Sets of deregulated microRNAs (miRNAs), termed miRNA signatures, are promising biomarkers for cancer. Validation of miRNA signatures requires a technique that is accurate, sensitive, capable of detecting multiple miRNAs, fast,...
4.
Ghasemi F, Wegman D, Kanoatov M, Yang B, Liu S, Yousef G, et al.
Anal Chem
. 2013 Oct;
85(21):10062-6.
PMID: 24127917
Studies suggest that patterns of deregulation in sets of microRNA (miRNA) can be used as cancer diagnostic and prognostic biomarkers. Establishing a "miRNA fingerprint"-based diagnostic technique requires a suitable miRNA...
5.
Wegman D, Cherney L, Yousef G, Krylov S
Anal Chem
. 2013 Jun;
85(13):6518-23.
PMID: 23742626
Using microRNA (miRNA) as molecular markers of diseases requires a method for accurate measurement of multiple miRNAs in biological samples. Direct quantitative analysis of multiple miRNAs (DQAMmiR) has been recently...
6.
Mazouchi A, Dodgson B, Wegman D, Krylov S, Gradinaru C
Analyst
. 2012 Oct;
137(23):5538-45.
PMID: 23085816
We report a simple method to efficiently couple on-column, standard Capillary Electrophoresis with Confocal MultiParameter Fluorescence detection (CE-CMPF) using only commercially available components. A molecular collection of 13% and a...
7.
Dodgson B, Mazouchi A, Wegman D, Gradinaru C, Krylov S
Anal Chem
. 2012 Jun;
84(13):5470-4.
PMID: 22697284
We report direct quantitative analysis of multiple miRNAs with a detection limit of 1000 copies without miRNA enrichment or modification. A 300-fold improvement over the previously published detection limit was...
8.
Woon E, Demetriades M, Bagg E, Aik W, Krylova S, Ma J, et al.
J Med Chem
. 2012 Jan;
55(5):2173-84.
PMID: 22263962
2-Oxoglutarate-dependent nucleic acid demethylases are of biological interest because of their roles in nucleic acid repair and modification. Although some of these enzymes are linked to physiology, their regulatory roles...
9.
Wegman D, Krylov S
Angew Chem Int Ed Engl
. 2011 Sep;
50(44):10335-9.
PMID: 21919168
No abstract available.
10.
Krylova S, Wegman D, Krylov S
Anal Chem
. 2010 May;
82(11):4428-33.
PMID: 20429579
A single-stranded DNA-binding protein (SSB) has been recently proven to facilitate highly efficient separation of the excess hybridization probe from the probe-target hybrid in gel-free capillary electrophoresis. SSB added to...