David W Morgens
Overview
Explore the profile of David W Morgens including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
41
Citations
2695
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Morgens D, Gulyas L, Mao X, Rivera-Madera A, Souza A, Glaunsinger B
Mol Syst Biol
. 2024 Nov;
21(1):30-58.
PMID: 39562742
Complex transcriptional control is a conserved feature of both eukaryotes and the viruses that infect them. Despite viral genomes being smaller and more gene dense than their hosts, we generally...
2.
Ruetz T, Pogson A, Kashiwagi C, Gagnon S, Morton B, Sun E, et al.
Nature
. 2024 Oct;
634(8036):1150-1159.
PMID: 39358505
Ageing impairs the ability of neural stem cells (NSCs) to transition from quiescence to proliferation in the adult mammalian brain. Functional decline of NSCs results in the decreased production of...
3.
Mathiowetz A, Meymand E, Deol K, Parlakgul G, Lange M, Pang S, et al.
bioRxiv
. 2024 Jun;
PMID: 38895340
Imbalances in lipid storage and secretion lead to the accumulation of hepatocyte lipid droplets (LDs) (i.e., hepatic steatosis). Our understanding of the mechanisms that govern the channeling of hepatocyte neutral...
4.
Gentile G, Poggio T, Catalano A, Voutilainen M, Lahnalampi M, Andrade-Martinez M, et al.
Blood Adv
. 2024 Apr;
8(11):2846-2860.
PMID: 38598725
The t(1;19) translocation, encoding the oncogenic fusion protein E2A (TCF3)-PBX1, is involved in acute lymphoblastic leukemia (ALL) and associated with a pre-B-cell receptor (preBCR+) phenotype. Relapse in patients with E2A-PBX1+...
5.
Colville A, Liu J, Rodriguez-Mateo C, Thomas S, Ishak H, Zhou R, et al.
Cell Metab
. 2023 Sep;
35(10):1814-1829.e6.
PMID: 37699398
Selectively ablating damaged cells is an evolving therapeutic approach for age-related disease. Current methods for genome-wide screens to identify genes whose deletion might promote the death of damaged or senescent...
6.
Roberts M, Deol K, Mathiowetz A, Lange M, Leto D, Stevenson J, et al.
Dev Cell
. 2023 Jul;
58(18):1782-1800.e10.
PMID: 37494933
Despite the key roles of perilipin-2 (PLIN2) in governing lipid droplet (LD) metabolism, the mechanisms that regulate PLIN2 levels remain incompletely understood. Here, we leverage a set of genome-edited human...
7.
Morgens D, Gulyas L, Rivera-Madera A, Souza A, Glaunsinger B
bioRxiv
. 2023 Jul;
PMID: 37461644
Complex transcriptional control is a conserved feature of both eukaryotes and the viruses that infect them. Here, we illustrate this by combining high-density functional genomics, expression profiling, and viral-specific chromosome...
8.
Ludwig C, Thurm A, Morgens D, Yang K, Tycko J, Bassik M, et al.
Cell Syst
. 2023 Jun;
14(6):482-500.e8.
PMID: 37348463
Viruses encode transcriptional regulatory proteins critical for controlling viral and host gene expression. Given their multifunctional nature and high sequence divergence, it is unclear which viral proteins can affect transcription...
9.
Mathiowetz A, Roberts M, Morgens D, Olzmann J, Li Z
STAR Protoc
. 2023 Mar;
4(2):102201.
PMID: 37000620
Phenotypic screens involving pooled CRISPR-Cas9 libraries offer a powerful, rapid yet affordable approach to evaluate gene functions on a global scale. Here, we present a protocol for performing pooled CRISPR-Cas9...
10.
Yoshinaga M, Han K, Morgens D, Horii T, Kobayashi R, Tsuruyama T, et al.
Nat Commun
. 2022 Oct;
13(1):6435.
PMID: 36307435
During erythroid differentiation, the maintenance of genome integrity is key for the success of multiple rounds of cell division. However, molecular mechanisms coordinating the expression of DNA repair machinery in...