David W Dorward
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Explore the profile of David W Dorward including associated specialties, affiliations and a list of published articles.
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61
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3350
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Recent Articles
1.
Fischer E, Hansen B, Nair V, Hoyt F, Schwartz C, Dorward D
Curr Protoc
. 2024 May;
4(5):e1034.
PMID: 38717581
Scanning electron microscopy (SEM) remains distinct in its ability to allow topographical visualization of structures. Key elements to consider for successful examination of biological specimens include appropriate preparative and imaging...
2.
Kaiser J, Liu X, Luongo C, Matsuoka Y, Santos C, Yang L, et al.
iScience
. 2023 Dec;
26(12):108490.
PMID: 38144450
Next-generation SARS-CoV-2 vaccines are needed that induce systemic and mucosal immunity. Murine pneumonia virus (MPV), a murine homolog of respiratory syncytial virus, is attenuated by host-range restriction in nonhuman primates...
3.
Perez-Valencia L, Vannella K, Ramos-Benitez M, Sun J, Abu-Asab M, Dorward D, et al.
iScience
. 2023 Aug;
26(8):107323.
PMID: 37529105
Lymphocyte depletion is a distinctive feature of Ebola virus (EBOV) disease. The ectodomain of EBOV glycoprotein (GP) is cleaved off the surface of infected cells into circulation as shed GP....
4.
Wachter J, Cheff B, Hillman C, Carracoi V, Dorward D, Martens C, et al.
Nat Commun
. 2023 Jan;
14(1):198.
PMID: 36639656
The alternative sigma factor RpoS plays a central role in the critical host-adaptive response of the Lyme disease spirochete, Borrelia burgdorferi. We previously identified bbd18 as a negative regulator of...
5.
Park H, Matsuoka Y, Luongo C, Yang L, Santos C, Liu X, et al.
NPJ Vaccines
. 2022 Jun;
7(1):72.
PMID: 35764659
Current vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are administered parenterally and appear to be more protective in the lower versus the upper respiratory tract. Vaccines are needed...
6.
Narasimhan P, Tariq S, Akabas L, Dorward D, Nutman T, Tolouei Semnani R
Am J Trop Med Hyg
. 2022 Feb;
106(4):1254-1262.
PMID: 35226872
Monocyte dysfunction in helminth infection is one of the mechanisms proposed to explain the diminished parasite antigen-specific T cell responses seen with patent filarial infection. In fact, monocytes from filariae-infected...
7.
Schmidt A, Fitzpatrick A, Schwartzkopf C, Faith D, Jennings L, Coluccio A, et al.
mBio
. 2022 Jan;
13(1):e0244121.
PMID: 35038902
Pseudomonas aeruginosa is an opportunistic pathogen that causes infections in a variety of settings. Many P. aeruginosa isolates are infected by filamentous Pf bacteriophage integrated into the bacterial chromosome as...
8.
Mlera L, Offerdahl D, Dorward D, Carmody A, Chiramel A, Best S, et al.
Emerg Microbes Infect
. 2021 Jun;
10(1):1378-1389.
PMID: 34162308
The vector-borne flaviviruses (VBFVs) are well known for causing great misery and death in humans worldwide. The VBFVs include those transmitted by mosquitos, such as Zika virus (ZIKV), dengue virus;...
9.
Ricciardi A, Bennuru S, Tariq S, Kaur S, Wu W, Elkahloun A, et al.
PLoS Negl Trop Dis
. 2021 Jan;
15(1):e0008884.
PMID: 33411714
We have previously shown that the microfilarial (mf) stage of Brugia malayi can inhibit the mammalian target of rapamycin (mTOR; a conserved serine/threonine kinase critical for immune regulation and cellular...
10.
Anton O, Peterson M, Hollander M, Dorward D, Arora G, Traba J, et al.
Proc Natl Acad Sci U S A
. 2019 Dec;
117(1):522-531.
PMID: 31871169
Interleukin 15 (IL-15) is an essential cytokine for the survival and proliferation of natural killer (NK) cells. IL-15 activates signaling by the β and common γ (γ) chain heterodimer of...