Scott D Kobayashi
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Explore the profile of Scott D Kobayashi including associated specialties, affiliations and a list of published articles.
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81
Citations
3885
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Recent Articles
1.
DeLeo F, Porter A, Kobayashi S, Freedman B, Hao M, Jiang J, et al.
mBio
. 2023 Sep;
14(5):e0194923.
PMID: 37671860
strains with a combination of multidrug resistance and hypervirulence genotypes (MDR hvKp) have emerged as a cause of human infections. The ability of these microbes to avoid killing by the...
2.
Collins M, Race B, Messer R, Baune C, Kobayashi S, Long D, et al.
J Surg Res
. 2022 Nov;
283:428-437.
PMID: 36434839
Introduction: The use of prosthetic mesh in hernia repair provides a powerful tool to increase repair longevity, decrease recurrence rates, and facilitate complex abdominal wall reconstruction. Overall infection rates with...
3.
Kobayashi S, DeLeo F, Quinn M
Immunol Rev
. 2022 Nov;
314(1):210-228.
PMID: 36345955
Neutrophils or polymorphonuclear neutrophils (PMNs) are an important component of innate host defense. These phagocytic leukocytes are recruited to infected tissues and kill invading microbes. There are several general characteristics...
4.
Opoku-Temeng C, Freedman B, Porter A, Kobayashi S, Chen L, Kreiswirth B, et al.
Microbiol Spectr
. 2022 Oct;
10(6):e0151722.
PMID: 36264264
Carbapenem-resistant Klebsiella pneumoniae isolates classified as multilocus sequence type 258 (ST258) are a problem in health care settings in many countries globally. ST258 isolates are resistant to multiple classes of...
5.
Malachowa N, McGuinness W, Kobayashi S, Porter A, Shaia C, Lovaglio J, et al.
Microbiol Spectr
. 2022 Apr;
10(2):e0271621.
PMID: 35389241
Staphylococcus aureus remains a leading cause of skin and soft tissue infections (SSTIs) globally. In the United States, many of these infections are caused by isolates classified as USA300. Our...
6.
Nguyen T, Cheung G, Rigby K, Kamenyeva O, Kabat J, Sturdevant D, et al.
Nat Microbiol
. 2021 Dec;
7(1):62-72.
PMID: 34873293
Swift recruitment of phagocytic leucocytes is critical in preventing infection when bacteria breach through the protective layers of the skin. According to canonical models, this occurs via an indirect process...
7.
Rungelrath V, Porter A, Malachowa N, Freedman B, Leung J, Voyich J, et al.
Microbiol Spectr
. 2021 Oct;
9(2):e0088821.
PMID: 34704790
Staphylococcus aureus is an important human pathogen that can cause a variety of diseases ranging from mild superficial skin infections to life-threatening conditions like necrotizing pneumonia, endocarditis, and septicemia. Polymorphonuclear...
8.
Innate Host Defense against Klebsiella pneumoniae and the Outlook for Development of Immunotherapies
Opoku-Temeng C, Malachowa N, Kobayashi S, DeLeo F
J Innate Immun
. 2021 Oct;
14(3):167-181.
PMID: 34628410
Klebsiella pneumoniae (K. pneumoniae) is a Gram-negative commensal bacterium and opportunistic pathogen. In healthy individuals, the innate immune system is adept at protecting against K. pneumoniae infection. Notably, the serum...
9.
Hesse S, Malachowa N, Porter A, Freedman B, Kobayashi S, Gardner D, et al.
mBio
. 2021 Feb;
12(1).
PMID: 33622728
Severe infections caused by multidrug-resistant sequence type 258 (ST258) highlight the need for new therapeutics with activity against this pathogen. Bacteriophage (phage) therapy is an alternative treatment approach for multidrug-resistant...
10.
Malachowa N, Kobayashi S, Porter A, Freedman B, Hanley P, Lovaglio J, et al.
mBio
. 2019 Dec;
10(6).
PMID: 31848292
is a human gut communal organism and notorious opportunistic pathogen. The relative high burden of asymptomatic colonization by is often compounded by multidrug resistance-a potential problem for individuals with significant...