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David W C Beasley

Explore the profile of David W C Beasley including associated specialties, affiliations and a list of published articles. Areas
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Articles 80
Citations 2382
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Recent Articles
1.
Lackritz E, Ng L, Marques E, Rabe I, Bourne N, Staples J, et al.
Lancet Infect Dis . 2025 Mar; PMID: 40024263
The 2015-16 Zika virus epidemic emerged in the Americas and rapidly spread throughout the region and beyond, showing the epidemic potential of this mosquito-borne Orthoflavivirus and its capacity to cause...
2.
Ostrowsky J, Katzelnick L, Bourne N, Barrett A, Thomas S, Diamond M, et al.
Lancet Infect Dis . 2025 Mar; PMID: 40024262
The 2015-16 Zika virus epidemic in the Americas drew global attention to Zika virus infection as a cause of microcephaly and Guillain-Barré syndrome. The epidemic highlighted the urgent need for...
3.
Kosulin K, Brasel T, Smith J, Torres M, Bitzer A, Dubischar K, et al.
Emerg Microbes Infect . 2025 Feb; 14(1):2469653. PMID: 39998495
Cross-neutralization is generally a prerequisite for cross-protection of vaccines against diseases caused by heterologous viruses. Using sera obtained from a randomized clinical phase 3 trial in adults, we investigated the...
4.
Johnson D, Juelich T, Zhang L, Smith J, Kalveram B, Perez D, et al.
Viruses . 2024 Jul; 16(7). PMID: 39066263
Favipiravir is a ribonucleoside analogue that has been explored as a therapeutic for the treatment of Ebola Virus Disease (EVD). Promising data from rodent models has informed nonhuman primate trials,...
5.
Lawrence W, Peel J, Slayden R, Peterson J, Baze W, Hensel M, et al.
Antimicrob Agents Chemother . 2024 Jun; 68(7):e0011224. PMID: 38888319
Inhalation anthrax is the most severe form of infection, often progressing to fatal conditions if left untreated. While recommended antibiotics can effectively treat anthrax when promptly administered, strains engineered for...
6.
Flandes X, Hansen C, Palani S, Abbas K, Bennett C, Caro W, et al.
Vaccine . 2024 Feb; 42(19S1):S9-S24. PMID: 38407992
Chikungunya virus (CHIKV) a mosquito-borne alphavirus is the causative agent of Chikungunya (CHIK), a disease with low mortality but high acute and chronic morbidity resulting in a high overall burden...
7.
Haila G, Plante J, Widen S, Beasley D
Microbiol Resour Announc . 2023 Oct; 12(11):e0042323. PMID: 37846978
Koutango virus (KOUV), a close relative of West Nile virus, is highly neuroinvasive in animal models and has been associated with human disease. The complete genome of the KOUV prototype...
8.
Thursz M, Sadiq F, Tree J, Karayiannis P, Beasley D, Dejnirattisai W, et al.
J Gen Virol . 2023 Jul; 104(7). PMID: 37493135
No abstract available.
9.
Thursz M, Sadiq F, Tree J, Karayiannis P, Beasley D, Dejnirattisai W, et al.
J Gen Virol . 2023 Jul; 104(7). PMID: 37432877
The 2',5'- oligoadenylate synthetase (OAS) - ribonuclease L (RNAseL) - phosphodiesterase 12 (PDE12) pathway is an essential interferon-induced effector mechanism against RNA virus infection. Inhibition of PDE12 leads to selective...
10.
Goethals O, Kaptein S, Kesteleyn B, Bonfanti J, Van Wesenbeeck L, Bardiot D, et al.
Nature . 2023 Mar; 615(7953):678-686. PMID: 36922586
Dengue is a major health threat and the number of symptomatic infections caused by the four dengue serotypes is estimated to be 96 million with annually around 10,000 deaths. However,...