David S Terman
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Explore the profile of David S Terman including associated specialties, affiliations and a list of published articles.
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10
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93
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Recent Articles
1.
Sun C, Wu L, Wankhede M, Wang D, Thoerner J, Woody L, et al.
JCI Insight
. 2019 Apr;
4(7).
PMID: 30944254
Hypoxic tumor niches are chief causes of treatment resistance and tumor recurrence. Sickle erythrocytes' (SSRBCs') intrinsic oxygen-sensing functionality empowers them to access such hypoxic niches wherein they form microaggregates that...
2.
Sun C, Wu L, Knopick P, Bradley D, Townes T, Terman D
Am J Hematol
. 2017 Jun;
92(10):981-988.
PMID: 28646491
Sickle erythrocytes' (SSRBCs) unique physical adaptation to hypoxic conditions renders them able to home to hypoxic tumor niches in vivo, shut down tumor blood flow and induce tumoricidal responses. SSRBCs...
3.
Sun C, Willmon C, Wu L, Knopick P, Thoerner J, Vile R, et al.
Front Oncol
. 2016 Jul;
6:166.
PMID: 27458571
Insights from the study of cancer resistance in animals have led to the discovery of novel anticancer pathways and opened new venues for cancer prevention and treatment. Sickle cells (SSRBCs)...
4.
Hodille E, Alekseeva L, Berkova N, Serrier A, Badiou C, Gilquin B, et al.
Front Microbiol
. 2016 May;
7:441.
PMID: 27148168
Maintenance of an intact epithelial barrier constitutes a pivotal defense mechanism against infections. Staphylococcus aureus is a versatile pathogen that produces multiple factors including exotoxins that promote tissue alterations. The...
5.
Terman D, Serier A, Dauwalder O, Badiou C, Dutour A, Thomas D, et al.
Front Cell Infect Microbiol
. 2013 Aug;
3:38.
PMID: 23964349
The egcSEs comprise five genetically linked staphylococcal enterotoxins, SEG, SEI, SElM, SElN, and SElO and two pseudotoxins which constitute an operon present in up to 80% of Staphylococcus aureus isolates....
6.
Choe S, Terman D, Rivers A, Rivera J, Lottenberg R, Sorg B
J Control Release
. 2013 Jul;
171(2):184-92.
PMID: 23871960
Selective drug delivery to hypoxic tumor niches remains a significant therapeutic challenge that calls for new conceptual approaches. Sickle red blood cells (SSRBCs) have shown an ability to target such...
7.
Terman D, Viglianti B, Zennadi R, Fels D, Boruta R, Yuan H, et al.
PLoS One
. 2013 Jan;
8(1):e52543.
PMID: 23326340
Resistance of hypoxic solid tumor niches to chemotherapy and radiotherapy remains a major scientific challenge that calls for conceptually new approaches. Here we exploit a hitherto unrecognized ability of sickled...
8.
Seo K, Park J, Terman D, Bohach G
J Transl Med
. 2010 Jan;
8:2.
PMID: 20070903
Background: Staphylococcal enterotoxins (SEs), SE-like (SEl) toxins, and toxic shock syndrome toxin-1 (TSST-1), produced by Staphylococcus aureus, belong to the subgroup of microbial superantigens (SAgs). SAgs induce clonal proliferation of...
9.
Terman D, Bohach G, Vandenesch F, Etienne J, Lina G, Sahn S
Clin Chest Med
. 2006 May;
27(2):321-34.
PMID: 16716821
There has been renewed interest in the superantigens as antitumor agents with the discovery of a group of bacterial superantigens known as the enterotoxin gene cluster (egc staphylococcal enterotoxins [SEs])....
10.
Ren S, Terman D, Bohach G, Silvers A, Hansen C, Colt H, et al.
Chest
. 2004 Nov;
126(5):1529-39.
PMID: 15539723
Background: Malignant pleural effusion (MPE) may occur in up to 50% of patients with non-small cell lung cancer (NSCLC). The majority of these patients have a poor performance status and...