David S Stephens
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Explore the profile of David S Stephens including associated specialties, affiliations and a list of published articles.
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142
Citations
5446
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Recent Articles
1.
Rodriguez E, Tzeng Y, Sannigrahi S, Stephens D
Infect Immun
. 2025 Feb;
93(3):e0035024.
PMID: 39902952
Over the last decade, a () urethritis-causing clade (UC) has emerged to cause clusters of meningococcal urethritis in the United States and globally. One genomic signature of UC is the...
2.
Rodriguez E, Tzeng Y, Berry I, Howie R, McNamara L, Stephens D
Clin Microbiol Rev
. 2025 Jan;
38(1):e0021524.
PMID: 39887238
SUMMARYThe human pathogen () is the causative agent of invasive meningococcal disease (IMD), usually presenting as meningitis, bacteremia, or sepsis. Unlike , antibiotic resistance in has developed slowly. However, in...
3.
Tzeng Y, Esposito D, Nederveld A, Hardison R, Carter A, Stephens D, et al.
J Infect Dis
. 2024 Dec;
PMID: 39657012
Background: Clusters of male urethritis cases, caused by a novel clade of non-groupable Neisseria meningitidis (NmUC, "the clade"), have been reported globally. Genetic features unique to NmUC isolates include: the...
4.
Tzeng Y, Sannigrahi S, Stephens D
NPJ Vaccines
. 2024 Nov;
9(1):223.
PMID: 39557897
The 4CMenB (Bexsero) vaccine contains detergent-extracted outer membrane vesicles (OMVs) from a Neisseria meningitidis (Nm) group B strain NZ98/254 and three recombinant Nm protein antigens: Neisseria adhesin A (NadA), Factor...
5.
Wu X, Alibayov B, Xiang X, Lattar S, Sakai F, Medders A, et al.
Drug Resist Updat
. 2024 Aug;
77:101138.
PMID: 39167981
Aims: To investigate the molecular events associated with acquiring macrolide resistance genes [mefE/mel (Mega) or ermB] in Streptococcus pneumoniae (Spn) during nasopharyngeal colonization. Methods And Results: Genomic analysis of 128...
6.
Tzeng Y, Sannigrahi S, Borrow R, Stephens D
Front Immunol
. 2024 Mar;
15:1350344.
PMID: 38440731
Introduction: Outer membrane vesicles (OMVs) of in the group B-directed vaccine MenB-4C (Bexsero) protect against infections with . The immunological basis for protection remains unclear. OMV vaccines generate human antibodies...
7.
Rodriguez E, Tzeng Y, Stephens D
Microb Genom
. 2023 Oct;
9(10).
PMID: 37850987
) is a bacterial pathogen responsible for invasive meningococcal disease. Though typically colonizing the nasopharynx, multiple outbreaks of meningococcal urethritis were first reported in 2015-2016; outbreaks originally presumed to be...
8.
Branche A, Rouphael N, Diemert D, Falsey A, Losada C, Baden L, et al.
Nat Med
. 2023 Aug;
29(9):2334-2346.
PMID: 37640860
Vaccine protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection wanes over time, requiring updated boosters. In a phase 2, open-label, randomized clinical trial with sequentially enrolled stages at...
9.
Lyke K, Atmar R, Dominguez Islas C, Posavad C, Deming M, Branche A, et al.
NPJ Vaccines
. 2023 Jul;
8(1):98.
PMID: 37433788
As part of a multicenter study evaluating homologous and heterologous COVID-19 booster vaccines, we assessed the magnitude, breadth, and short-term durability of binding and pseudovirus-neutralizing antibody (PsVNA) responses following a...
10.