David S King
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Explore the profile of David S King including associated specialties, affiliations and a list of published articles.
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51
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4401
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Recent Articles
1.
Reekes T, Higginson C, Sigvardt K, King D, Levine D, Wheelock V, et al.
J Int Neuropsychol Soc
. 2023 Mar;
29(9):813-820.
PMID: 36971238
Objectives: This study aims to address a gap in the data on cognitive sex differences in persons living with Parkinson disease (PD). There is some evidence that cognitive dysfunction is...
2.
Tugwell B, King D, Kaiser S
Can J Diabetes
. 2019 Sep;
44(3):216-218.
PMID: 31494032
No abstract available.
3.
de Oliveira Mann C, Orzalli M, King D, Kagan J, Lee A, Kranzusch P
Cell Rep
. 2019 Apr;
27(4):1165-1175.e5.
PMID: 31018131
Stimulator of interferon genes (STING) is a key regulator of type I interferon and pro-inflammatory responses during infection, cellular stress, and cancer. Here, we reveal a mechanism for how STING...
4.
Whiteley A, Eaglesham J, de Oliveira Mann C, Morehouse B, Lowey B, Nieminen E, et al.
Nature
. 2019 Feb;
567(7747):194-199.
PMID: 30787435
Cyclic dinucleotides (CDNs) have central roles in bacterial homeostasis and virulence by acting as nucleotide second messengers. Bacterial CDNs also elicit immune responses during infection when they are detected by...
5.
Brejc K, Bian Q, Uzawa S, Wheeler B, Anderson E, King D, et al.
Cell
. 2017 Sep;
171(1):85-102.e23.
PMID: 28867287
Chromatin modification and higher-order chromosome structure play key roles in gene regulation, but their functional interplay in controlling gene expression is elusive. We have discovered the machinery and mechanism underlying...
6.
Loftus K, Cui H, Coutavas E, King D, Ceravolo A, Pereiras D, et al.
Cell Cycle
. 2017 Jul;
16(15):1414-1429.
PMID: 28723232
Centromere protein F (CENP-F) is a component of the kinetochore and a regulator of cell cycle progression. CENP-F recruits the dynein transport machinery and orchestrates several cell cycle-specific transport events,...
7.
Kim A, Ulirsch J, Wilmes S, Unal E, Moraga I, Karakukcu M, et al.
Cell
. 2017 Mar;
168(6):1053-1064.e15.
PMID: 28283061
Cytokines are classically thought to stimulate downstream signaling pathways through monotonic activation of receptors. We describe a severe anemia resulting from a homozygous mutation (R150Q) in the cytokine erythropoietin (EPO)....
8.
Su X, Ditlev J, Hui E, Xing W, Banjade S, Okrut J, et al.
Science
. 2016 Apr;
352(6285):595-9.
PMID: 27056844
Activation of various cell surface receptors triggers the reorganization of downstream signaling molecules into micrometer- or submicrometer-sized clusters. However, the functional consequences of such clustering have been unclear. We biochemically...
9.
Silverman J, Greene N, King D, Heldwein E
J Virol
. 2012 May;
86(15):8171-84.
PMID: 22623783
Herpes simplex virus type 1 (HSV-1) enters cells by fusion of its envelope with a host cell membrane, which requires four viral glycoproteins and a cellular receptor. Viral fusion glycoprotein...
10.
Li P, Banjade S, Cheng H, Kim S, Chen B, Guo L, et al.
Nature
. 2012 Mar;
483(7389):336-40.
PMID: 22398450
Cells are organized on length scales ranging from ångström to micrometres. However, the mechanisms by which ångström-scale molecular properties are translated to micrometre-scale macroscopic properties are not well understood. Here...