David S Goldstein
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Explore the profile of David S Goldstein including associated specialties, affiliations and a list of published articles.
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271
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8768
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Recent Articles
1.
Parveen S, Alam P, Orru C, Vascellari S, Hughson A, Zou W, et al.
NPJ Biosens
. 2025 Feb;
2(1):8.
PMID: 39950033
Parkinson's disease (PD), dementia with Lewy bodies (DLB), and other synucleinopathies are characterized by the accumulation of abnormal, self-propagating aggregates of α-synuclein. RT-QuIC or seed amplification assays are currently showing...
2.
Goldstein D, Alam P, Sullivan P, Holmes C, Gelsomino J, Hughson A, et al.
Mov Disord Clin Pract
. 2025 Jan;
PMID: 39817492
Background: Cerebrospinal fluid (CSF) α-synuclein seeding activity (SSA) via a seed amplification assay might predict central Lewy body diseases (LBD) in at-risk individuals. Objective: The aim was to assess CSF...
3.
Isonaka R, Sullivan P, Goldstein D
Neurology
. 2025 Jan;
104(3):e210215.
PMID: 39805051
Background And Objectives: Lewy body diseases (LBDs) such as Parkinson disease (PD) feature increased deposition of α-synuclein (α-syn) in cutaneous sympathetic noradrenergic nerves. The pathophysiologic significance of sympathetic intraneuronal α-syn...
4.
Goldstein D, Sullivan P, Holmes C
Clin Auton Res
. 2024 Dec;
PMID: 39656385
Background: Autonomic synucleinopathies feature autonomic failure and intracellular deposition of the protein alpha-synuclein. Three such conditions are the Lewy body diseases (LBDs) Parkinson's disease (PD) and pure autonomic failure (PAF)...
5.
Goldstein D, Mina Y, Walitt B, Sullivan P, Enose-Akahata Y, Jacobson S, et al.
Neurology
. 2024 Aug;
103(6):e209742.
PMID: 39173103
Objectives: After acute coronavirus disease-2019 (COVID-19), people often experience fatigue, "brain fog," or other central neurologic symptoms (neuro-post-acute SARS-CoV2, or "Neuro-PASC"). In this observational study we evaluated whether abnormalities noted...
6.
Goldstein D, Sullivan P, Holmes C
J Neurochem
. 2024 Jun;
168(9):2926-2934.
PMID: 38943336
The synucleinopathies Parkinson disease (PD), multiple system atrophy (MSA), and the Lewy body form of pure autonomic failure (PAF) entail intra-cytoplasmic deposition of the protein alpha-synuclein and pathogenic catecholaminergic neurodegeneration....
7.
Isonaka R, Sullivan P, Holmes C, Goldstein D
Clin Auton Res
. 2024 Jun;
34(3):329-339.
PMID: 38844644
Purpose: Neurogenic orthostatic hypotension (nOH) results from deficient reflexive delivery of norepinephrine to cardiovascular receptors in response to decreased cardiac venous return. Lewy body (LB) forms of nOH are characterized...
8.
Heiss J, Ray-Chaudhury A, Kleiner D, Ehrlich D, Scott G, Edwards N, et al.
Mov Disord
. 2024 May;
39(8):1412-1417.
PMID: 38718138
Objective: Gene therapy by convection-enhanced delivery of type 2 adeno-associated virus-glial cell derived neurotrophic factor (AAV2-GDNF) to the bilateral putamina seeks to increase GDNF gene expression and treat Parkinson's disease...
9.
Isonaka R, Sullivan P, Holmes C, Goldstein D
Res Sq
. 2024 Mar;
PMID: 38529504
Purpose: Neurogenic orthostatic hypotension (nOH) results from deficient reflexive delivery of norepinephrine to cardiovascular receptors in response to decreased cardiac venous return. Lewy body (LB) forms of nOH entail low...
10.
Grabov E, Sullivan P, Wang S, Goldstein D
Clin Auton Res
. 2024 Mar;
34(1):125-135.
PMID: 38446362
Purpose: Orthostasis increases the variability of continuously recorded blood pressure (BP). Low-frequency (LF) BP oscillations (Mayer waves) in this setting are related to the vascular-sympathetic baroreflex. Mechanisms of increased high-frequency...