David Rysanek
Overview
Explore the profile of David Rysanek including associated specialties, affiliations and a list of published articles.
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11
Citations
86
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Recent Articles
1.
Chrienova Z, Rysanek D, Novak J, Vasicova P, Oleksak P, Andrys R, et al.
Biomed Pharmacother
. 2025 Feb;
184:117883.
PMID: 39924415
No abstract available.
2.
Oleksak P, Rysanek D, Vancurova M, Vasicova P, Urbancokova A, Novak J, et al.
ACS Pharmacol Transl Sci
. 2024 Sep;
7(9):2755-2783.
PMID: 39296273
6-Nitrobenzo[]thiophene 1,1-dioxide (Stattic) is a potent signal transducer and activator of the transcription 3 (STAT3) inhibitor developed originally for anticancer therapy. However, Stattic harbors several STAT3 inhibition-independent biological effects. To...
3.
Chrienova Z, Rysanek D, Novak J, Vasicova P, Oleksak P, Andrys R, et al.
Biomed Pharmacother
. 2023 Oct;
167:115600.
PMID: 37783152
Frentizole is immunosuppressive drug with low acute toxicity and lifespan-prolonging effect. Recently, frentizole´s potential to disrupt toxic amyloid β (Aβ) - Aβ-binding alcohol dehydrogenase (ABAD) interaction in mitochondria in Alzheimer´s...
4.
Mikyskova R, Sapega O, Psotka M, Novotny O, Hodny Z, Balintova S, et al.
Mol Med Rep
. 2023 Feb;
27(4).
PMID: 36825563
Signal transducer and activator of transcription 3 (STAT3) signalling serves an important role in carcinogenesis and cellular senescence, and its inhibition in tumour cells represents an attractive therapeutic target. Premature...
5.
Chrienova Z, Rysanek D, Oleksak P, Stary D, Bajda M, Reinis M, et al.
Front Aging Neurosci
. 2022 Dec;
14:1048260.
PMID: 36561137
To date, the most studied drug in anti-aging research is the mTOR inhibitor - rapamycin. Despite its almost perfect anti-aging profile, rapamycin exerts one significant limitation - inappropriate physicochemical properties....
6.
Rysanek D, Vasicova P, Kolla J, Sedlak D, Andera L, Bartek J, et al.
Aging (Albany NY)
. 2022 Aug;
14(16):6381-6414.
PMID: 35951353
Accumulation of senescent cells in tissues with advancing age participates in the pathogenesis of several human age-associated diseases. Specific senescent secretome, the resistance of senescent cells to apoptotic stimuli, and...
7.
Oleksak P, Psotka M, Vancurova M, Sapega O, Bieblova J, Reinis M, et al.
J Enzyme Inhib Med Chem
. 2021 Jan;
36(1):410-424.
PMID: 33440995
Twelve novel analogs of STAT3 inhibitor BP-1-102 were designed and synthesised with the aim to modify hydrophobic fragments of the molecules that are important for interaction with the STAT3 SH2...
8.
Pichrtova M, Holzinger A, Kulichova J, Rysanek D, Soljakova T, Trumhova K, et al.
Eur J Phycol
. 2018 Nov;
53(4):492-508.
PMID: 30487730
Filamentous conjugating green microalgae (Zygnematophyceae, Streptophyta) belong to the most common primary producers in polar hydro-terrestrial environments such as meltwater streamlets and shallow pools. The mats formed by these organisms...
9.
Pierangelini M, Rysanek D, Lang I, Adlassnig W, Holzinger A
Planta
. 2017 Jul;
246(5):971-986.
PMID: 28721563
The basal streptophyte Klebsormidium and the advanced Zygnema show adaptation to terrestrialization. Differences are found in photoprotection and resistance to short-term light changes, but not in CO acquisition. Streptophyte green...
10.
Rysanek D, Holzinger A, Skaloud P
Phycologia
. 2016 Jun;
55(4):347-358.
PMID: 27293301
Our knowledge of the processes involved in speciation of microalgae remains highly limited. In the present study, we investigated a potential role of ecological speciation processes in diversification of the...