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David Rudd

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Articles 24
Citations 192
Followers 0
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Recent Articles
1.
Malhotra A, Dehghankelishadi P, Kaur I, Marshall M, Rudd D, Wojnilowicz M, et al.
ACS Appl Mater Interfaces . 2025 Jan; 17(4):5955-5969. PMID: 39804251
Common treatment approaches for triple-negative breast cancer (TNBC) are associated with severe side effects due to the unfavorable biodistribution profile of potent chemotherapeutics. Here, we explored the potential of TNBC-targeting...
2.
Deore P, Tsang Min Ching S, Nitschke M, Rudd D, Brumley D, Hinde E, et al.
J Exp Bot . 2024 Apr; 75(13):4005-4023. PMID: 38636949
The thermal tolerance of symbiodiniacean photo-endosymbionts largely underpins the thermal bleaching resilience of their cnidarian hosts such as corals and the coral model Exaiptasia diaphana. While variation in thermal tolerance...
3.
Chan W, Meyers L, Rudd D, Topa S, van Oppen M
Glob Chang Biol . 2023 Nov; 29(24):6945-6968. PMID: 37913765
Ocean warming has caused coral mass bleaching and mortality worldwide and the persistence of symbiotic reef-building corals requires rapid acclimation or adaptation. Experimental evolution of the coral's microalgal symbionts followed...
4.
Krishnan S, Winkler D, Creek D, Anderson D, Kirana C, Maddern G, et al.
Metabolomics . 2023 Sep; 19(10):84. PMID: 37731020
Introduction: Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide. Alteration in lipid metabolism and chemokine expression are considered hallmark characteristics of malignant progression and metastasis of CRC....
5.
Tong Z, Esser L, Galettis P, Rudd D, Easton C, Nilghaz A, et al.
Biosensors (Basel) . 2023 Aug; 13(8). PMID: 37622865
Microfluidic technology is applied across various research areas including organ-on-chip (OOC) systems. The main material used for microfluidics is polydimethylsiloxane (PDMS), a silicone elastomer material that is biocompatible, transparent, and...
6.
Kaur I, Tieu T, Deepagan V, Ali M, Alsunaydih F, Rudd D, et al.
Pharmaceutics . 2023 May; 15(5). PMID: 37242631
Despite the clinical benefits that chemotherapeutics has had on the treatment of breast cancer, drug resistance remains one of the main obstacles to curative cancer therapy. Nanomedicines allow therapeutics to...
7.
Chan W, Rudd D, van Oppen M
Life Sci Alliance . 2023 May; 6(8). PMID: 37202120
Microbial symbionts frequently localize within specific body structures or cell types of their multicellular hosts. This spatiotemporal niche is critical to host health, nutrient exchange, and fitness. Measuring host-microbe metabolite...
8.
Mahbub P, Hasan C, Rudd D, Voelcker N, Orbell J, Cole I, et al.
Anal Chim Acta . 2023 Apr; 1255:341156. PMID: 37032060
Organic peroxide explosives (OPEs) are unstable, non-military, contemporary security threats often found in improvised explosive devices. Chemiluminescence (CL) can be used to detect OPEs, via radical formation consisting of peroxide...
9.
Lu J, Zhu Y, Parkington H, Hussein M, Zhao J, Bergen P, et al.
Mol Neurobiol . 2022 Nov; 60(3):1317-1330. PMID: 36443617
Intraventricular or intrathecal administration of polymyxins are increasingly used to treat multidrug-resistant (MDR) Gram-negative bacteria caused infections in the central nervous system (CNS). However, our limited knowledge of the mechanisms...
10.
Mehta A, Desai A, Rudd D, Siddiqui G, Nowell C, Tong Z, et al.
Adv Biol (Weinh) . 2022 Aug; 6(12):e2200152. PMID: 35999436
A continuous, sealed endothelial membrane is essential for the blood-brain barrier (BBB) to protect neurons from toxins present in systemic circulation. Endothelial cells are critical sensors of the capillary environment,...