David R Ghasemi
Overview
Explore the profile of David R Ghasemi including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
173
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Recent Articles
1.
Velz J, Freudenmann L, Medici G, Dubbelaar M, Mohme M, Ghasemi D, et al.
Nat Commun
. 2025 Feb;
16(1):1364.
PMID: 39904979
Medulloblastoma is the most frequent malignant primary brain tumor in children. Despite recent advances in integrated genomics, the prognosis in children with high-risk medulloblastoma remains devastating, and new tumor-specific therapeutic...
2.
Smirnov P, Przybilla M, Simovic-Lorenz M, Parra R, Susak H, Ratnaparkhe M, et al.
Nat Commun
. 2025 Jan;
16(1):1085.
PMID: 39870666
No abstract available.
3.
Okonechnikov K, Ghasemi D, Schrimpf D, Tonn S, Mynarek M, Koster J, et al.
Acta Neuropathol Commun
. 2025 Jan;
13(1):4.
PMID: 39762990
Recent genomic studies have allowed the subdivision of intracranial ependymomas into molecularly distinct groups with highly specific clinical features and outcomes. The majority of supratentorial ependymomas (ST-EPN) harbor ZFTA-RELA fusions...
4.
Smirnov P, Przybilla M, Simovic-Lorenz M, Parra R, Susak H, Ratnaparkhe M, et al.
Nat Commun
. 2024 Nov;
15(1):10183.
PMID: 39580568
Chromothripsis is a frequent form of genome instability, whereby a presumably single catastrophic event generates extensive genomic rearrangements of one or multiple chromosome(s). However, little is known about the heterogeneity...
5.
Ghasemi D, Okonechnikov K, Rademacher A, Tirier S, Maass K, Schumacher H, et al.
Nat Commun
. 2024 Oct;
15(1):8597.
PMID: 39366943
No abstract available.
6.
Gold M, Ong W, Masteller A, Ghasemi D, Galindo J, Park N, et al.
Nat Commun
. 2024 Jan;
15(1):270.
PMID: 38191555
Many genes that drive normal cellular development also contribute to oncogenesis. Medulloblastoma (MB) tumors likely arise from neuronal progenitors in the cerebellum, and we hypothesized that the heterogeneity observed in...
7.
Ghasemi D, Okonechnikov K, Rademacher A, Tirier S, Maass K, Schumacher H, et al.
Nat Commun
. 2024 Jan;
15(1):269.
PMID: 38191550
Medulloblastomas with extensive nodularity are cerebellar tumors characterized by two distinct compartments and variable disease progression. The mechanisms governing the balance between proliferation and differentiation in MBEN remain poorly understood....
8.
Chapman R, Ghasemi D, Andreiuolo F, Zschernack V, Tauziede Espariat A, Buttarelli F, et al.
Neuro Oncol
. 2023 Mar;
25(10):1871-1882.
PMID: 36916248
Background: Accurate identification of brain tumor molecular subgroups is increasingly important. We aimed to establish the most accurate and reproducible ependymoma subgroup biomarker detection techniques, across 147 cases from International...
9.
Ghasemi D, Fleischhack G, Milde T, Pajtler K
Cancers (Basel)
. 2022 Feb;
14(3).
PMID: 35158947
Medulloblastoma is an embryonal pediatric brain tumor and can be divided into at least four molecularly defined groups. The category non-WNT/non-SHH medulloblastoma summarizes medulloblastoma groups 3 and 4 and is...
10.
Shatara M, Schieffer K, Klawinski D, Thomas D, Pierson C, Sribnick E, et al.
Acta Neuropathol Commun
. 2021 Dec;
9(1):192.
PMID: 34895332
Primary spinal cord tumors contribute to ≤ 10% of central nervous system tumors in individuals of pediatric or adolescent age. Among intramedullary tumors, spinal ependymomas make up ~ 30% of...