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David R Danforth

Explore the profile of David R Danforth including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Mintz K, Danforth D, Ruiz T
Pathogens . 2024 Feb; 13(2). PMID: 38392837
Infective endocarditis (IE), a disease of the endocardial surface of the heart, is usually of bacterial origin and disproportionally affects individuals with underlying structural heart disease. Although IE is typically...
2.
Danforth D, Melloni M, Thorpe R, Cohen A, Voogt R, Tristano J, et al.
Mol Oral Microbiol . 2023 Nov; 38(6):471-488. PMID: 37941494
Protein glycosylation is critical to the quaternary structure and collagen-binding activity of the extracellular matrix protein adhesin A (EmaA) associated with Aggregatibacter actinomycetemcomitans. The glycosylation of this large, trimeric autotransporter...
3.
Tristano J, Danforth D, Wargo M, Mintz K
Mol Oral Microbiol . 2023 Mar; 38(3):237-250. PMID: 36871155
Aggregatibacter actinomycetemcomitans is a gram-negative bacterium associated with periodontal disease and a variety of disseminated extra-oral infections. Tissue colonization is mediated by fimbriae and non-fimbriae adhesins resulting in the formation...
4.
Tang-Siegel G, Danforth D, Tristano J, Ruiz T, Mintz K
Microbiology (Reading) . 2022 May; 168(5). PMID: 35551696
, a causative agent of periodontitis and non-oral diseases, synthesizes a trimeric extracellular matrix protein adhesin A (EmaA) that mediates collagen binding and biofilm formation. EmaA is found as two...
5.
Danforth D, Melloni M, Tristano J, Mintz K
Mol Oral Microbiol . 2021 Jun; 36(4):243-253. PMID: 34085776
Aggregatibacter actinomycetemcomitans is a Gram-negative bacterium associated with periodontal disease and multiple disseminated extra-oral infections. Colonization of these distinct physiological niches is contingent on the expression of specific surface proteins...
6.
Danforth D, Tang-Siegel G, Ruiz T, Mintz K
Infect Immun . 2018 Oct; 87(1). PMID: 30297525
Periodontitis is an inflammatory disease caused by polymicrobial biofilms. The periodontal pathogen displays two proteinaceous surface structures, the fimbriae and the nonfimbrial extracellular matrix binding protein A (EmaA), as observed...