David R Corey
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Explore the profile of David R Corey including associated specialties, affiliations and a list of published articles.
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Articles
151
Citations
5788
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Recent Articles
1.
Corey D
Nucleic Acid Ther
. 2024 Nov;
35(1):1-5.
PMID: 39570673
The recent Nobel Prizes awarded to Ambros and Ruvkun have refocused attention on microRNAs (miRNAs). The importance of miRNAs for basic science has always been clear, but the application to...
2.
Johnson K, Kilikevicius A, Hofman C, Hu J, Liu Y, Aguilar S, et al.
Nucleic Acids Res
. 2023 Dec;
52(4):1930-1952.
PMID: 38109320
Argonaute protein is associated with post-transcriptional control of cytoplasmic gene expression through miRNA-induced silencing complexes (miRISC). Specific cellular and environmental conditions can trigger AGO protein to accumulate in the nucleus....
3.
Belgrad J, Fakih H, Johnson K, Corey D
Nucleic Acids Res
. 2023 Nov;
52(2):511-512.
PMID: 38035373
No abstract available.
4.
Hu J, Shen X, Kheirabadi M, Streeter M, Qian Z, Mootha V, et al.
ACS Omega
. 2023 Nov;
8(45):42797-42802.
PMID: 38024683
Fuchs' corneal endothelial dystrophy (FECD) is a major cause of vision loss. Corneal transplantation is the only effective curative treatment, but this surgery has limitations. A pharmacological intervention would complement...
5.
Hu J, Gong X, Fan Y, Aguilar S, Rigo F, Prakash T, et al.
Nucleic Acid Ther
. 2023 Nov;
33(6):339-347.
PMID: 37917066
One advantage of antisense oligonucleotides (ASOs) for drug development is their long-lasting gene knockdown after administration . In this study, we examine the effect on gene expression after intraocular injection...
6.
Hofman C, Corey D
Cell Chem Biol
. 2023 Oct;
31(1):125-138.
PMID: 37804835
Synthetic antisense oligonucleotides (ASOs) and duplex RNAs (dsRNAs) are an increasingly successful strategy for drug development. After a slow start, the pace of success has accelerated since the approval of...
7.
Johnson K, Kilikevicius A, Hofman C, Hu J, Liu Y, Aguilar S, et al.
bioRxiv
. 2023 Jul;
PMID: 37461596
Argonaute protein is associated with post-transcriptional control of cytoplasmic gene expression through miRNA-induced silencing complexes (miRISC). Specific cellular and environmental conditions can trigger AGO protein to accumulate in the nucleus....
8.
Hu J, Gong X, Johnson S, Corey D, Mootha V
Invest Ophthalmol Vis Sci
. 2023 May;
64(5):16.
PMID: 37204786
Purpose: In the United States, 70% of Fuchs' endothelial corneal dystrophy (FECD) cases are caused by an intronic trinucleotide repeat expansion in the TCF4 gene. CUG repeat RNA transcripts from...
9.
Johnson K, Johnson S, Liu J, Chu Y, Arana C, Han Y, et al.
RNA
. 2023 May;
29(8):1166-1184.
PMID: 37169394
The potential for microRNAs (miRNAs) to regulate gene expression remains incompletely understood. DROSHA initiates the biogenesis of miRNAs while variants of Argonaute (AGO) and trinucleotide repeat containing six (TNRC6) family...
10.
Johnson K, Corey D
RNA
. 2023 Jan;
29(4):415-422.
PMID: 36657971
RNA interference is almost always associated with post-transcriptional silencing in the cytoplasm. MicroRNAs (miRNAs) and critical RNAi protein factors like argonaute (AGO) and trinucleotide repeat binding containing 6 protein (TNRC6),...