David R Barn
Overview
Explore the profile of David R Barn including associated specialties, affiliations and a list of published articles.
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2
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1
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Recent Articles
1.
Cowley P, Baker J, Barn D, Buchanan K, Carlyle I, Clark J, et al.
Bioorg Med Chem Lett
. 2010 Nov;
21(1):497-501.
PMID: 21075628
The discovery and structure-activity relationship of a novel series of indole-2-carboxamide antagonists of the cannabinoid CB(1) receptor is disclosed. Compound 26i was found to be a high potency, selective cannabinoid...
2.
Palin R, Barn D, Clark J, Cottney J, Cowley P, Crockatt M, et al.
Bioorg Med Chem Lett
. 2005 Jan;
15(3):589-93.
PMID: 15664818
A series of 3-phenoxypropyl piperidine analogues have been discovered as novel ORL1 receptor agonists. Structure-activity relationships have been explored around the 3-phenoxypropyl region with several potent and selective analogues identified.