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David Pflieger

Explore the profile of David Pflieger including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 674
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Recent Articles
1.
Pouclet A, Pflieger D, Merret R, Carpentier M, Schiaffini M, Zuber H, et al.
Plant Cell . 2024 Jun; 36(9):3674-3688. PMID: 38869231
Decapping is a crucial step in mRNA degradation in eucaryotes and requires the formation of a holoenzyme complex between the decapping enzyme DECAPPING 2 (DCP2) and the decapping enhancer DCP1....
2.
Giraudo P, Simonnot Q, Pflieger D, Peter J, Gagliardi D, Zuber H
Methods Mol Biol . 2023 Oct; 2723:233-252. PMID: 37824074
Deadenylation is a major process that regulates gene expression by shaping the length of mRNA poly(A) tails. Deadenylation is controlled by factors in trans that recruit or impede deadenylases, by...
3.
Elser D, Pflieger D, Villette C, Moegle B, Miesch L, Gaquerel E
Sci Adv . 2023 Aug; 9(34):eade8984. PMID: 37624884
Specialized metabolite (SM) diversification is a core process to plants' adaptation to diverse ecological niches. Here, we implemented a computational mass spectrometry-based metabolomics approach to exploring SM diversification in tissues...
4.
Ndecky S, Nguyen T, Eiche E, Cognat V, Pflieger D, Pawar N, et al.
J Exp Bot . 2023 Mar; 74(10):3220-3239. PMID: 36879437
Plant responses to salt exposure involve large reconfigurations of hormonal pathways that orchestrate physiological changes towards tolerance. Jasmonate (JA) hormones are essential to withstand biotic and abiotic assaults, but their...
5.
Cognat V, Pawlak G, Pflieger D, Drouard L
Plant J . 2022 Oct; 112(4):1112-1119. PMID: 36196656
PlantRNA (http://plantrna.ibmp.cnrs.fr/) is a comprehensive database of transfer RNA (tRNA) gene sequences retrieved from fully annotated nuclear, plastidial and mitochondrial genomes of photosynthetic organisms. In the first release (PlantRNA 1.0),...
6.
Scheer H, de Almeida C, Ferrier E, Simonnot Q, Poirier L, Pflieger D, et al.
Nat Commun . 2021 Feb; 12(1):1298. PMID: 33637717
Uridylation is a widespread modification destabilizing eukaryotic mRNAs. Yet, molecular mechanisms underlying TUTase-mediated mRNA degradation remain mostly unresolved. Here, we report that the Arabidopsis TUTase URT1 participates in a molecular...
7.
Pitzalis N, Amari K, Graindorge S, Pflieger D, Donaire L, Wassenegger M, et al.
Commun Biol . 2020 Nov; 3(1):702. PMID: 33230160
Virus-induced plant diseases in cultivated plants cause important damages in yield. Although the mechanisms of virus infection are intensely studied at the cell biology level, only little is known about...
8.
Hummel G, Berr A, Graindorge S, Cognat V, Ubrig E, Pflieger D, et al.
Nucleic Acids Res . 2020 Sep; 48(18):10297-10312. PMID: 32941623
Beyond their key role in translation, cytosolic transfer RNAs (tRNAs) are involved in a wide range of other biological processes. Nuclear tRNA genes (tDNAs) are transcribed by the RNA polymerase...
9.
Bohrer M, Rymen B, Himber C, Gerbaud A, Pflieger D, Laudencia-Chingcuanco D, et al.
Methods Mol Biol . 2020 Jul; 2166:387-411. PMID: 32710422
Cells have sophisticated RNA-directed mechanisms to regulate genes, destroy viruses, or silence transposable elements (TEs). In terrestrial plants, a specialized non-coding RNA machinery involving RNA polymerase IV (Pol IV) and...
10.
Brion C, Caradec C, Pflieger D, Friedrich A, Schacherer J
Mol Biol Evol . 2020 May; 37(9):2520-2530. PMID: 32359150
To explore the origin of the diversity observed in natural populations, many studies have investigated the relationship between genotype and phenotype. In yeast species, especially in Saccharomyces cerevisiae, these studies...