David Ornelles
Overview
Explore the profile of David Ornelles including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
9
Citations
141
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, et al.
mSphere
. 2023 Jan;
8(2):e0003423.
PMID: 36700653
Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease...
2.
Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, et al.
mBio
. 2023 Jan;
14(1):e0018823.
PMID: 36700642
Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease...
3.
Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, et al.
J Virol
. 2023 Jan;
97(2):e0008923.
PMID: 36700640
Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease...
4.
Kaverina N, Kadagidze Z, Borovjagin A, Karseladze A, Kim C, Lesniak M, et al.
Oncogene
. 2018 Jul;
37(46):6069-6082.
PMID: 29991800
Autophagy is an evolutionarily conserved process regulating cellular homeostasis via digestion of dysfunctional proteins and whole cellular organelles by mechanisms, involving their enclosure into double-membrane vacuoles that are subsequently fused...
5.
Kute T, Stehle Jr J, Ornelles D, Walker N, Delbono O, Vaughn J
Oncoimmunology
. 2012 Nov;
1(6):810-821.
PMID: 23162748
Use of the antibody trastuzumab to kill HER2+ breast cancer cells is an attractive therapy because of its specificity and minimal adverse effects. However, a large fraction of HER2+ positive...
6.
Hart L, Ornelles D, Koumenis C
J Biol Chem
. 2006 Dec;
282(9):6061-7.
PMID: 17172468
Adenoviral proteins interact with host-cell proteins to either exploit or inhibit cellular functions for the purpose of viral propagation. E4orf6, the 34-kDa gene product of the E4 gene, interacts with...
7.
Hart L, Yannone S, Naczki C, Orlando J, Waters S, Akman S, et al.
J Biol Chem
. 2004 Oct;
280(2):1474-81.
PMID: 15507430
The adenoviral protein E4orf6 has been shown to inhibit both in vitro V(D)J recombination and adenoviral DNA concatenation, two processes that rely on cellular DNA double strand break repair (DSBR)...
8.
McNees A, Mahr J, Ornelles D, Gooding L
J Virol
. 2004 Jun;
78(13):6955-66.
PMID: 15194772
Detection of adenovirus DNA in human tonsillar T cells in the absence of active virus replication suggests that T cells may be a site of latency or of attenuated virus...
9.
Schaack J, Bennett M, Colbert J, Torres A, Clayton G, Ornelles D, et al.
Proc Natl Acad Sci U S A
. 2004 Feb;
101(9):3124-9.
PMID: 14976240
Replication-defective human adenovirus (Ad) group C transducing vectors, most of which have the E1A, E1B, and E3 genes deleted, are highly inflammatory despite the fact that the parental viruses typically...