David Orlicky
Overview
Explore the profile of David Orlicky including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
285
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Recent Articles
1.
Graham L, Su L, Nicklawsky A, Feng F, Orlicky D, Petraccione J, et al.
Cancers (Basel)
. 2025 Feb;
17(4).
PMID: 40002188
The use of supraphysiologic testosterone, particularly when alternated with an anti-androgen agent in men with metastatic castration-resistant prostate cancer (CRPC), has demonstrated promising results in clinical trials. As the use...
2.
Uppalapati S, Kant S, Liu L, Kim J, Orlicky D, McClelland M, et al.
Science
. 2024 Apr;
384(6691):100-105.
PMID: 38574144
Phage viruses shape the evolution and virulence of their bacterial hosts. The genome encodes several stress-inducible prophages. The Gifsy-1 prophage terminase protein, whose canonical function is to process phage DNA...
3.
Loh L, Orlicky D, Spengler A, Levens C, Celli S, Domenico J, et al.
bioRxiv
. 2023 Dec;
PMID: 38076996
Background & Aims: Lymphocytes that produce IL-17 can confer protective immunity during infections by pathogens, yet their involvement in inflammatory diseases is a subject of debate. Although these cells may...
4.
Iwanaga R, Truong B, Hsu J, Lambert K, Vyas R, Orlicky D, et al.
Mol Carcinog
. 2020 Jun;
59(9):1052-1063.
PMID: 32562448
Melanoma is an aggressive, deadly skin cancer derived from melanocytes, a neural crest cell derivative. Melanoma cells mirror the developmental program of neural crest cells in that they exhibit the...
5.
Pollitt K, Kim J, Peccia J, Elimelech M, Zhang Y, Charkoftaki G, et al.
Sci Total Environ
. 2019 Jul;
690:853-866.
PMID: 31302550
1,4-Dioxane has historically been used to stabilize chlorinated solvents and more recently has been found as a contaminant of numerous consumer and food products. Once discharged into the environment, its...
6.
McGettigan B, McMahan R, Orlicky D, Burchill M, Danhorn T, Francis P, et al.
Hepatology
. 2018 Dec;
70(1):67-83.
PMID: 30516830
A crucial component of nonalcoholic fatty liver disease (NAFLD) pathogenesis is lipid stress, which may contribute to hepatic inflammation and activation of innate immunity in the liver. However, little is...
7.
Bednarek J, Traxinger B, Brigham D, Roach J, Orlicky D, Wang D, et al.
Hepatology
. 2018 Apr;
68(5):1890-1904.
PMID: 29679373
Biliary atresia (BA) is a neonatal T cell-mediated, inflammatory, sclerosing cholangiopathy. In the rhesus rotavirus (RRV)-induced neonatal mouse model of BA (murine BA), mice lacking B cells do not develop...
8.
Cree-Green M, Scalzo R, Harrall K, Newcomer B, Schauer I, Huebschmann A, et al.
Diabetes
. 2018 Apr;
67(7):1369-1379.
PMID: 29643061
Type 2 diabetes is associated with impaired exercise capacity. Alterations in both muscle perfusion and mitochondrial function can contribute to exercise impairment. We hypothesized that impaired muscle mitochondrial function in...
9.
Wang X, Wang D, Luo Y, Myakala K, Dobrinskikh E, Rosenberg A, et al.
J Am Soc Nephrol
. 2017 Nov;
29(1):118-137.
PMID: 29089371
Bile acids are ligands for the nuclear hormone receptor farnesoid X receptor (FXR) and the G protein-coupled receptor TGR5. We have shown that FXR and TGR5 have renoprotective roles in...
10.
Saben J, Bales E, Jackman M, Orlicky D, MacLean P, McManaman J
PLoS One
. 2014 May;
9(5):e98066.
PMID: 24849657
Maternal metabolic and nutrient trafficking adaptations to lactation differ among lean and obese mice fed a high fat (HF) diet. Obesity is thought to impair milk lipid production, in part,...