David Meek
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Explore the profile of David Meek including associated specialties, affiliations and a list of published articles.
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17
Citations
528
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Recent Articles
1.
Craig C, Johnston J, Goodley P, Bishop P, Al-Najjar H, Brown L, et al.
JTO Clin Res Rep
. 2024 Aug;
5(8):100694.
PMID: 39161961
Introduction: Single-station N2 (ssN2) versus multi-station N2 has been used as a selection criterion for treatment recommendations between surgical versus non-surgical multimodality treatment in stage III-N2 NSCLC. We hypothesized that...
2.
Cai F, Watson B, Meek D, Huhman D, Wherritt D, Ben C, et al.
J Chem Ecol
. 2017 Jul;
43(7):712-724.
PMID: 28744732
Plant resistance mechanisms to insect herbivory can potentially be bred into crops as an important strategy for integrated pest management. Medicago truncatula ecotypes inoculated with the rhizobium Ensifer medicae (Sinorhizobium...
3.
OMahony J, Marrie R, Laporte A, Yeh E, Bar-Or A, Phan C, et al.
Pediatrics
. 2015 Jun;
136(1):e115-23.
PMID: 26034241
Background: Few prospective studies have systematically evaluated the extent of recovery from incident acquired demyelinating syndromes (ADS) of the central nervous system in children. Methods: In a national cohort study...
4.
Chan K, Meek D, Chakravorty I
J Med Case Rep
. 2011 Jul;
5:314.
PMID: 21756329
Introduction: Myocarditis is rarely reported as an extra-pulmonary manifestation of influenza while pregnancy is a rare cause of cardiomyopathy. Pregnancy was identified as a major risk factor for increased mortality...
5.
Banwell B, Bar-Or A, Arnold D, Sadovnick D, Narayanan S, McGowan M, et al.
Lancet Neurol
. 2011 Apr;
10(5):436-45.
PMID: 21459044
Background: HLA-DRB1*15 genotype, previous infection with Epstein-Barr virus, and vitamin D insufficiency are susceptibility factors for multiple sclerosis, but whether they act synergistically to increase risk is unknown. We aimed...
6.
Lai K, Leong W, Chau J, Jia D, Zeng L, Liu H, et al.
EMBO J
. 2010 Jul;
29(17):2994-3006.
PMID: 20657550
p53 mediates DNA damage-induced cell-cycle arrest, apoptosis, or senescence, and it is controlled by Mdm2, which mainly ubiquitinates p53 in the nucleus and promotes p53 nuclear export and degradation. By...
7.
Meek D, Chakravorty I
Practitioner
. 2010 Jan;
253(1723):17-20, 2.
PMID: 20043505
In OSA, the patient suffers repeated episodes of apnoea caused by narrowing or closure of the pharyngeal airway during sleep. The degree of closure of the airway leads to periods...
8.
Ochocka A, Kampanis P, Nicol S, Allende-Vega N, Cox M, Marcar L, et al.
FEBS Lett
. 2009 Jan;
583(4):621-6.
PMID: 19166840
The p53 tumour suppressor protein is tightly controlled by the E3 ubiquitin ligase, mouse double minute 2 (MDM2), but maintains MDM2 expression as part of a negative feedback loop. We...
9.
Allende-Vega N, McKenzie L, Meek D
Mol Cell Biochem
. 2008 Jun;
316(1-2):99-106.
PMID: 18548200
Induction and activation of the p53 tumour suppressor protein occurs in response to a number of cellular stresses, including disruption of RNA polymerase II-mediated transcription. Both p53 itself and its...
10.
Hogan C, Hutchison C, Marcar L, Milne D, Saville M, Goodlad J, et al.
J Biol Chem
. 2008 May;
283(26):18012-23.
PMID: 18467333
Mutation of the p53 gene is a common event during tumor pathogenesis. Other mechanisms, such as mdm2 amplification, provide alternative routes through which dysfunction of the p53 pathway is promoted....