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David Meder

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Articles 18
Citations 360
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Recent Articles
1.
Chen Thomsen B, Vinding M, Meder D, Marner L, Lokkegaard A, Siebner H
Neuroimage Clin . 2024 Nov; 44:103705. PMID: 39577332
Parkinson's disease (PD) can be effectively treated with levodopa and dopamine agonists but leads to levodopa-induced dyskinesia (LID) in most patients in the long run. Various functional brain mapping techniques...
2.
Lohse A, Lokkegaard A, Siebner H, Meder D
J Neurosci . 2023 Jan; 43(8):1414-1421. PMID: 36650059
Impulsivity refers to the tendency to act prematurely or without forethought, and excessive impulsivity is a key problem in many neuropsychiatric disorders. Since the pre-supplementary motor area (pre-SMA) has been...
3.
Nilsson S, Meder D, Madsen K, Toni I, Siebner H
Front Psychol . 2022 Nov; 13:989495. PMID: 36329745
People are better at approaching appetitive cues signaling reward and avoiding aversive cues signaling punishment than vice versa. This action bias has previously been shown in approach-avoidance tasks involving arm...
4.
Thorup A, Hemager N, Bliksted V, Greve A, Ohland J, Wilms M, et al.
Front Psychiatry . 2022 Apr; 13:809807. PMID: 35444571
Background: Children born to parents with severe mental illness have gained more attention during the last decades because of increasing evidence documenting that these children constitute a population with an...
5.
Madelung C, Meder D, Fuglsang S, Marques M, Boer V, Madsen K, et al.
Mov Disord . 2022 Feb; 37(3):479-489. PMID: 35114035
Background: Parkinson's disease (PD) causes a loss of neuromelanin-positive, noradrenergic neurons in the locus coeruleus (LC), which has been implicated in nonmotor dysfunction. Objectives: We used "neuromelanin sensitive" magnetic resonance...
6.
Meder D, Rabe F, Morville T, Madsen K, Koudahl M, Dolan R, et al.
PLoS Comput Biol . 2021 Sep; 17(9):e1009217. PMID: 34499635
Ergodicity describes an equivalence between the expectation value and the time average of observables. Applied to human behaviour, ergodic theories of decision-making reveal how individuals should tolerate risk in different...
7.
Herz D, Meder D, Camilleri J, Eickhoff S, Siebner H
Mov Disord . 2021 Jan; 36(5):1180-1190. PMID: 33427336
Background: Motor-related brain activity in Parkinson's disease has been investigated in a multitude of functional neuroimaging studies, which often yielded apparently conflicting results. Our previous meta-analysis did not resolve inconsistencies...
8.
Lohse A, Meder D, Nielsen S, Lund A, Herz D, Lokkegaard A, et al.
Brain Commun . 2020 Nov; 2(2):fcaa147. PMID: 33225277
Levodopa-induced dyskinesia gradually emerges during long-term dopamine therapy, causing major disability in patients with Parkinson disease. Using pharmacodynamic functional MRI, we have previously shown that the intake of levodopa triggers...
9.
Haagensen B, Herz D, Meder D, Madsen K, Lokkegaard A, Siebner H
Neuroimage Clin . 2020 Jul; 27:102330. PMID: 32688307
Dopaminergic treatment may impair the ability to suppress impulsive behaviours in patients with Parkinson's disease, triggering impulse control disorders. It is unclear how dopaminergic medication affects the neural networks that...
10.
Betts M, Kirilina E, Otaduy M, Ivanov D, Acosta-Cabronero J, Callaghan M, et al.
Brain . 2019 Jul; 142(9):2558-2571. PMID: 31327002
Pathological alterations to the locus coeruleus, the major source of noradrenaline in the brain, are histologically evident in early stages of neurodegenerative diseases. Novel MRI approaches now provide an opportunity...