David Mark Davies
Overview
Explore the profile of David Mark Davies including associated specialties, affiliations and a list of published articles.
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4
Citations
94
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Recent Articles
1.
Champion J, Dodd K, Lam H, Alzahrani M, Seifan S, Rad E, et al.
Cancers (Basel)
. 2022 Dec;
14(24).
PMID: 36551683
Therapies with the mechanistic target of rapamycin complex 1 (mTORC1) inhibitors are not fully curative for tuberous sclerosis complex (TSC) patients. Here, we propose that some mTORC1-independent disease facets of...
2.
Malorni L, Tyekucheva S, Hilbers F, Ignatiadis M, Neven P, Colleoni M, et al.
Eur J Cancer
. 2022 Feb;
164:39-51.
PMID: 35172272
Background: Biomarkers for cyclin-dependent kinase 4/6 inhibitors, such as palbociclib, for patients with hormone receptor-positive/HER2-negative metastatic breast cancer are lacking. Thymidine kinase is a proliferation marker downstream of the cyclin-dependent...
3.
Yan M, Gingras M, Dunlop E, Nouet Y, Dupuy F, Jalali Z, et al.
J Clin Invest
. 2014 Apr;
124(6):2640-50.
PMID: 24762438
The Warburg effect is a tumorigenic metabolic adaptation process characterized by augmented aerobic glycolysis, which enhances cellular bioenergetics. In normal cells, energy homeostasis is controlled by AMPK; however, its role...
4.
Dunlop E, Dodd K, Land S, Davies P, Martins N, Stuart H, et al.
Eur J Hum Genet
. 2011 Mar;
19(7):789-95.
PMID: 21407264
Tuberous sclerosis complex (TSC) is a genetic condition characterized by the growth of benign tumours in multiple organs, including the brain and kidneys, alongside intellectual disability and seizures. Identification of...