David M Eckmann
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Explore the profile of David M Eckmann including associated specialties, affiliations and a list of published articles.
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114
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1423
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Recent Articles
1.
Hossain T, Secor J, Eckmann D
Chem Biol Interact
. 2024 Oct;
404:111266.
PMID: 39426659
Hyperoxic exposure lasting days alters mitochondrial bioenergetic and dynamic functions in pulmonary cells as indices of oxygen toxicity. The aim of this study was to examine effects of short duration...
2.
Piper B, Bogamuwa S, Hossain T, Farkas D, Rosas L, Green A, et al.
J Clin Invest
. 2023 Nov;
134(3).
PMID: 38015641
Pulmonary arterial hypertension (PAH) is a devastating and progressive disease with limited treatment options. Endothelial dysfunction plays a central role in the development and progression of PAH, yet the underlying...
3.
Hossain T, Eckmann D
Life Sci
. 2023 Jun;
328:121880.
PMID: 37356749
Aims: Pulmonary oxygen toxicity is caused by exposure to a high fraction of inspired oxygen, which damages multiple cell types within the lung. The cellular basis for pulmonary oxygen toxicity...
4.
Piper B, Bogamuwa S, Hossain T, Farkas D, Rosas L, Green A, et al.
bioRxiv
. 2023 Feb;
PMID: 36778418
Pulmonary arterial hypertension (PAH) is a devastating and progressive disease with limited treatment options. Endothelial dysfunction plays a central role in development and progression of PAH, yet the underlying mechanisms...
5.
Green A, Hossain T, Eckmann D
Front Cell Dev Biol
. 2022 Nov;
10:1010232.
PMID: 36340034
Mitochondria are cell organelles that play pivotal roles in maintaining cell survival, cellular metabolic homeostasis, and cell death. Mitochondria are highly dynamic entities which undergo fusion and fission, and have...
6.
Farokhirad S, Kutti Kandy S, Tsourkas A, Ayyaswamy P, Eckmann D, Radhakrishnan R
Adv Mater Interfaces
. 2022 Jul;
8(23).
PMID: 35782961
How nanoparticle (NP) mechanical properties impact multivalent ligand-receptor-mediated binding to cell surfaces, the avidity, propensity for internalization, and effects due to crowding remains unknown or unquantified. Through computational analyses, the...
7.
Green A, Hossain T, Eckmann D
Life Sci
. 2021 May;
278:119616.
PMID: 34015286
Aims: Hyperbaric oxygen therapy (HBOT), used to promote wound healing, has limited efficacy in many clinical conditions. Wound healing exerts bioenergetic demands on cells that can exceed their intrinsic bioenergetic...
8.
Pancaro C, Purtell J, LaBuda D, Saager L, Klumpner T, Dubovoy T, et al.
Anesth Analg
. 2021 Apr;
133(1):151-159.
PMID: 33835077
Background: While flexible epidural catheters reduce the risk of paresthesia and intravascular cannulation, they may be more challenging to advance beyond the tip of a Tuohy needle. This may increase...
9.
Owiredu S, Ranganathan A, Greenwood J, Piel S, Janowska J, Eckmann D, et al.
Toxicol Rep
. 2020 Oct;
7:1263-1271.
PMID: 33005568
The objective of this study was to compare the use of hydroxocobalamin (B12a) and a succinate prodrug to evaluate for improvement in mitochondrial function in an model of cyanide poisoning....
10.
Eckmann D, Bradley R, Kandy S, Patil K, Janmey P, Radhakrishnan R
Curr Opin Struct Biol
. 2020 Jul;
64:104-110.
PMID: 32731155
Nanoparticle (NP)-based imaging and drug delivery systems for systemic (e.g. intravenous) therapeutic and diagnostic applications are inherently a complex integration of biology and engineering. A broad range of length and...