David L Stachura
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Explore the profile of David L Stachura including associated specialties, affiliations and a list of published articles.
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36
Citations
1704
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Recent Articles
1.
Feng H, Stachura D, White R, Gutierrez A, Zhang L, Sanda T, et al.
Cancer Cell
. 2024 Jun;
42(6):1130-1131.
PMID: 38861925
No abstract available.
2.
Namit A, Dowell W, Matiasek S, Webster J, Stachura D
PLoS One
. 2022 Mar;
17(3):e0265618.
PMID: 35333877
In November 2018, the Camp Fire devastated the mountain community of Paradise, CA. The burning of plastic pipes, wiring, construction materials, paint, and car batteries released toxic chemicals into the...
3.
Thapa S, Stachura D
Bioinform Biol Insights
. 2021 Aug;
15:11779322211037770.
PMID: 34413636
Neutrophils are a type of white blood cell essential for the function of the innate immune system. To elucidate mechanisms of neutrophil biology, many studies are performed in vertebrate animal...
4.
Rueb K, Stachura D
J Vis Exp
. 2021 May;
(170).
PMID: 33999034
The diversity of cell lineages that comprise mature blood in vertebrate animals arise from the differentiation of hematopoietic stem and progenitor cells (HSPCs). This is a critical process that occurs...
5.
Belmonte R, Engbretson I, Kim J, Cajias I, Ahn E, Stachura D
PLoS One
. 2021 Feb;
16(2):e0247489.
PMID: 33630943
The gene SON is on human chromosome 21 (21q22.11) and is thought to be associated with hematopoietic disorders that accompany Down syndrome. Additionally, SON is an RNA splicing factor that...
6.
Lewis T, Smith J, Griffin K, Aguiar S, Rueb K, Holmberg-Douglas N, et al.
PLoS One
. 2020 Aug;
15(8):e0236839.
PMID: 32780746
The majority of chronic myeloid leukemia (CML) cases are caused by a chromosomal translocation linking the breakpoint cluster region (BCR) gene to the Abelson murine leukemia viral oncogene-1 (ABL1), creating...
7.
Kim J, Park E, Chitayat D, Stachura D, Schaper J, Lindstrom K, et al.
Kidney Int
. 2019 Apr;
95(6):1494-1504.
PMID: 31005274
Although genetic testing is increasingly used in clinical nephrology, a large number of patients with congenital abnormalities of the kidney and urinary tract (CAKUT) remain undiagnosed with current gene panels....
8.
Nfe2 is dispensable for early but required for adult thrombocyte formation and function in zebrafish
Rost M, Shestopalov I, Liu Y, Vo A, Richter C, Emly S, et al.
Blood Adv
. 2018 Dec;
2(23):3418-3427.
PMID: 30504234
The NFE2 transcription factor is expressed in multiple hematopoietic lineages with a well-defined role in regulating megakaryocyte biogenesis and platelet production in mammals. Mice deficient in NFE2 develop severe thrombocytopenia...
9.
Berrun A, Harris E, Stachura D
PLoS One
. 2018 May;
13(5):e0196872.
PMID: 29758043
Hematopoiesis is an essential and highly regulated biological process that begins with hematopoietic stem cells (HSCs). In healthy organisms, HSCs are responsible for generating a multitude of mature blood cells...
10.
Liu C, Han T, Stachura D, Wang H, Vaisman B, Kim J, et al.
Nat Commun
. 2018 Apr;
9(1):1310.
PMID: 29615667
Lipoprotein lipase (LPL) mediates hydrolysis of triglycerides (TGs) to supply free fatty acids (FFAs) to tissues. Here, we show that LPL activity is also required for hematopoietic stem progenitor cell...