David L Boucher
Overview
Explore the profile of David L Boucher including associated specialties, affiliations and a list of published articles.
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8
Citations
239
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0
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Recent Articles
1.
White J, Hu L, Boucher D, Sutcliffe J
Mol Imaging Biol
. 2017 Jun;
20(1):103-113.
PMID: 28653240
Purpose: Increased expression of the αβ integrin correlates with advanced tumor grade and poor clinical outcome, identifying αβ as a prognostic indicator and an attractive target for molecular imaging. This...
2.
White J, Boucher D, Zettlitz K, Wu A, Sutcliffe J
Nucl Med Biol
. 2015 Sep;
42(12):945-57.
PMID: 26341848
Introduction: This work describes the development and characterization of two antibody fragments that specifically target the α(v)β(6) integrin, a non-covalent diabody and a disulfide-stabilized cys-diabody. The diabodies were analyzed for...
3.
Tsai H, Boucher D, Martinez A, Tepper C, Kung H
PLoS One
. 2012 Dec;
7(11):e49887.
PMID: 23209612
Recent studies identifying putative truncated androgen receptor isoforms with ligand-independent activity have shed new light on the acquisition of androgen depletion independent (ADI) growth of prostate cancer. In this study,...
4.
Boucher D, Chen J, Cherry S, Borowsky A
PLoS One
. 2012 Jun;
7(6):e39350.
PMID: 22745739
As the field of molecular imaging evolves and increasingly is asked to fill the discovery and validation space between basic science and clinical applications, careful consideration should be given to...
5.
Mitchell G, Gill R, Boucher D, Li C, Cherry S
Philos Trans A Math Phys Eng Sci
. 2011 Oct;
369(1955):4605-19.
PMID: 22006909
Cerenkov radiation is a phenomenon where optical photons are emitted when a charged particle moves faster than the speed of light for the medium in which it travels. Recently, we...
6.
Aweda T, Eskandari V, Kukis D, Boucher D, Marquez B, Beck H, et al.
Bioconjug Chem
. 2011 Jul;
22(8):1479-83.
PMID: 21755984
We describe the synthesis and development of new reactive DOTA-metal complexes for covalently targeting engineered receptors in vivo, which have superior tumor uptake and clearance properties for biomedical applications. These...
7.
Ma A, Xia L, Desai S, Boucher D, Guan Y, Shih H, et al.
Cancer Res
. 2006 Sep;
66(17):8439-47.
PMID: 16951154
Androgen receptor (AR) is a ligand-induced transcriptional factor, which plays an important role in the normal development of prostate as well as in the progression of prostate cancer. Numerous coactivators,...
8.
Tepper C, Boucher D, Ryan P, Ma A, Xia L, Lee L, et al.
Cancer Res
. 2002 Nov;
62(22):6606-14.
PMID: 12438256
CWR22 has been a valuable xenograft model for the study of prostate cancer progression from an androgen-dependent tumor to one that grows in castrated animals. Herein, we report the identification...