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David Kepplinger

Explore the profile of David Kepplinger including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Leonard J, Kepplinger D, Torres E, Hu C, Veneziano R, Hoemann C
Thromb Res . 2024 Nov; 244:109202. PMID: 39546984
Introduction: Acute respiratory distress syndrome (ARDS) patients are at risk of thrombosis through mechanisms implicating oxidized low-density lipoprotein (oxLDL). Endothelial cells, immune cells and platelets were reported to express scavenger...
2.
Minciunescu A, Rosner C, Kepplinger D, Del Castillo T, Overbeck D, Levy W, et al.
JACC Heart Fail . 2024 Jun; 12(8):1487-1493. PMID: 38934962
Guideline-directed medical therapy utilization in patients with heart failure with reduced ejection fraction (HFrEF) remains low despite benefits in morbidity and mortality. The authors describe a unique quality improvement initiative...
3.
Chang J, Kepplinger D, Metter E, Kim Y, Trankiem C, Felbaum D, et al.
Neurosurgery . 2024 Feb; 95(2):297-304. PMID: 38376157
Background And Objectives: Severe traumatic brain injury (sTBI) represents a diffuse, heterogeneous disease where therapeutic targets for optimizing clinical outcome remain unclear. Mean pressure reactivity index (PRx) values have demonstrated...
4.
Tehrani B, Sherwood M, Damluji A, Epps K, Bakhshi H, Cilia L, et al.
J Am Heart Assoc . 2024 Feb; 13(4):e031504. PMID: 38353242
Background: Distal transradial access (dTRA) is an alternative to conventional forearm transradial access (fTRA) for coronary angiography (CAG). Differences in healing of the radial artery (RA) in the forearm have...
5.
Vasas V, Lowell M, Villa J, Jamison Q, Siegle A, Katta P, et al.
PLoS Biol . 2024 Jan; 22(1):e3002444. PMID: 38261631
Plants, animals, and fungi display a rich tapestry of colors. Animals, in particular, use colors in dynamic displays performed in spatially complex environments. Although current approaches for studying colors are...
6.
Leonard J, Kepplinger D, Espina V, Gillevet P, Ke Y, Birukov K, et al.
J Thromb Haemost . 2023 Dec; 22(4):1031-1045. PMID: 38135253
Background: Blood clots are living tissues that release inflammatory mediators including IL-8/CXCL8 and MCP-1/CCL2. A deeper understanding of blood clots is needed to develop new therapies for prothrombotic disease states...
7.
Tehrani B, Sherwood M, Damluji A, Epps K, Bakhshi H, Cilia L, et al.
medRxiv . 2023 Jul; PMID: 37461583
Background: Distal transradial access (dTRA) is an alternative to conventional forearm transradial access (fTRA) for coronary angiography (CAG). Differences in healing of the radial artery in the forearm (FRA) have...
8.
Chang J, Kepplinger D, Metter E, Felbaum D, Mai J, Armonda R, et al.
J Neurol Sci . 2023 Jun; 450:120691. PMID: 37267816
Background: Pressure reactivity index (PRx) utilizes moving correlation coefficients from intracranial pressure (ICP) and mean arterial pressures to evaluate cerebral autoregulation. We evaluated patients with poor-grade subarachnoid hemorrhage (SAH), identified...
9.
Kepplinger D, Cohen Freue G
Methods Mol Biol . 2022 Oct; 2426:315-331. PMID: 36308695
Adaptive PENSE is a method that can be used to build models for predicting clinical outcomes from a small subset of a potentially large number of candidate proteins. Adaptive PENSE...
10.
Kepplinger D, Takhar M, Sasaki M, Hollander Z, Smith D, McManus B, et al.
PLoS One . 2017 Jun; 12(5):e0177569. PMID: 28562641
The quantitation of proteins using shotgun proteomics has gained popularity in the last decades, simplifying sample handling procedures, removing extensive protein separation steps and achieving a relatively high throughput readout....