David J Miller
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Explore the profile of David J Miller including associated specialties, affiliations and a list of published articles.
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306
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5312
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Recent Articles
1.
Leiva C, Torda G, Zhou C, Pan Y, Harris J, Xiang X, et al.
Glob Chang Biol
. 2025 Mar;
31(3):e70103.
PMID: 40028829
The semienclosed Bouraké lagoon in New Caledonia is a natural system that enables observation of evolution in action with respect to stress tolerance in marine organisms, a topic directly relevant...
2.
Soto-Heras S, Volz L, Bovin N, Miller D
Sci Rep
. 2025 Feb;
15(1):4680.
PMID: 39920342
During transport through the oviduct, sperm interact with epithelial cells by attaching to specific glycans, a mechanism believed to select sperm and prolong their viability. An in vitro model of...
3.
Phillips C, Burstyn I, Miller D, Hamade A, Avanasi R, Boon D, et al.
Glob Epidemiol
. 2024 Oct;
8:100167.
PMID: 39435396
One of the practical contributions of epidemiology studies is to inform risk assessment and management to protect public health. However, there is a perception among some that environmental and occupational...
4.
OBrien P, Robbins S, Tan S, Rix L, Miller D, Webster N, et al.
Environ Microbiol
. 2024 Sep;
26(9):e16690.
PMID: 39228053
Sponge microbiomes are often highly diverse making it difficult to determine which lineages are important for maintaining host health and homeostasis. Characterising genomic traits associated with symbiosis can improve our...
5.
Srivastava P, Johns S, Voice A, Morley K, Escorcia A, Miller D, et al.
ACS Catal
. 2024 Jul;
14(14):11034-11043.
PMID: 39050902
Engineering sesquiterpene synthases to form predefined alternative products is a major challenge due to their diversity in cyclization mechanisms and our limited understanding of how amino acid changes affect the...
6.
Zhang J, Schneller N, Field M, Chan C, Miller D, Strugnell J, et al.
Mol Ecol
. 2024 Jul;
33(16):e17468.
PMID: 39046252
The future survival of coral reefs in the Anthropocene depends on the capacity of corals to adapt as oceans warm and extreme weather events become more frequent. Targeted interventions designed...
7.
Gonzalez Requena V, Srivastava P, Miller D, Allemann R
Chembiochem
. 2024 Jul;
25(23):e202400290.
PMID: 39031755
The high-fidelity sesquiterpene cyclase (-)-germacradien-4-ol synthase (GdolS) converts farnesyl diphosphate into the macrocyclic alcohol (-)-germacradien-4-ol. Site-directed mutagenesis was used to decipher the role of key residues in the water control...
8.
Srivastava P, Johnson L, Miller D, Allemann R
Methods Enzymol
. 2024 Jun;
699:207-230.
PMID: 38942504
Chemoenzymatic synthesis of non-natural terpenes using the promiscuous activity of terpene synthases allows for the expansion of the chemical space of terpenoids with potentially new bioactivities. In this report, we...
9.
Mason B, Hayward D, Moya A, Cooke I, Sorenson A, Brunner R, et al.
Curr Biol
. 2024 Jun;
34(14):3226-3232.e5.
PMID: 38942019
A dynamic mucous layer containing numerous micro-organisms covers the surface of corals and has multiple functions including both removal of sediment and "food gathering." It is likely to also act...
10.
Discovery and first-time disclosure of CVN766, an exquisitely selective orexin 1 receptor antagonist
Glen A, Burli R, Livermore D, Buffham W, Merison S, Rowland A, et al.
Bioorg Med Chem Lett
. 2024 Jan;
100:129629.
PMID: 38295907
Modulators of orexin receptors are being developed for neurological illnesses such as sleep disorders, addictive behaviours and other psychiatric diseases. We herein describe the discovery of CVN766, a potent orexin...