David J Kemble
Overview
Explore the profile of David J Kemble including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
266
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Recent Articles
1.
Zhang X, Upputuri P, Coughlan M, Kemble D, Khan U, Zakharov Y, et al.
Opt Lett
. 2024 Dec;
50(1):33-36.
PMID: 39718846
It can be difficult to employ optical techniques for analyzing biological structures smaller than or comparable to the wavelength of light, such as extracellular vesicles or some types of bacteria....
2.
Kemble D, Lamothe S, Uhl L
Clin Biochem
. 2021 Mar;
92:82-85.
PMID: 33713635
Immunoassays are commonly used by the clinical laboratory, but paraproteins can occasionally produce erroneous results. In this study, we investigated the cause of apparent false positive results for multiple Kinetic...
3.
Kemble D, Brunelle A, Boulanger J, Cervinski M, Nerenz R
J Appl Lab Med
. 2021 Feb;
2(1):132-133.
PMID: 33636960
No abstract available.
4.
Kemble D, Jackson T, Morrison M, Cervinski M, Nerenz R
J Appl Lab Med
. 2021 Feb;
2(3):345-355.
PMID: 33636837
Background: Graves disease is caused by autoantibodies that target the thyroid-stimulating hormone receptor (TSHR). Anti-TSHR autoantibody measurement is routinely performed to differentiate between Graves disease and other causes of hyperthyroidism....
5.
Rodrigue B, Lamothe S, Kemble D
J Appl Lab Med
. 2020 Sep;
6(2):560-564.
PMID: 32995853
No abstract available.
6.
Kemble D, Cervinski M
J Appl Lab Med
. 2020 May;
5(2):300-310.
PMID: 32445388
Background: Rapid identification and quantification of toxic alcohols and ethylene glycol is imperative for appropriate treatment. Clinical laboratories frequently rely on direct injection gas chromatography (GC) methods, but these methods...
7.
Herskovits A, Kemble D, Uhl L
Int Anesthesiol Clin
. 2020 Feb;
58(2):12-18.
PMID: 32004170
No abstract available.
8.
Chen L, Marsiglia W, Chen H, Katigbak J, Erdjument-Bromage H, Kemble D, et al.
Nat Chem Biol
. 2020 Jan;
16(3):267-277.
PMID: 31959966
A long-standing mystery shrouds the mechanism by which catalytically repressed receptor tyrosine kinase domains accomplish transphosphorylation of activation loop (A-loop) tyrosines. Here we show that this reaction proceeds via an...
9.
Kemble D, McCullough L, Whitby F, Formosa T, Hill C
Mol Cell
. 2015 Oct;
60(2):294-306.
PMID: 26455391
FACT, a heterodimer of Spt16 and Pob3, is an essential histone chaperone. We show that the H2A-H2B binding activity that is central to FACT function resides in short acidic regions...
10.
Kemble D, Whitby F, Robinson H, McCullough L, Formosa T, Hill C
J Biol Chem
. 2013 Feb;
288(15):10188-94.
PMID: 23417676
The histone chaperone FACT is an essential and abundant heterodimer found in all eukaryotes. Here we report a crystal structure of the middle domain of the large subunit of FACT...