David J Grunwald
Overview
Explore the profile of David J Grunwald including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
15
Citations
835
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Jurynec M, Gavile C, Honeggar M, Ma Y, Veerabhadraiah S, Novak K, et al.
Ann Rheum Dis
. 2022 Jun;
81(10):1465-1473.
PMID: 35732460
Objectives: How inflammatory signalling contributes to osteoarthritis (OA) susceptibility is undetermined. An allele encoding a hyperactive form of the Receptor Interacting Protein Kinase 2 (RIPK2) proinflammatory signalling intermediate has been...
2.
Arveseth C, Happ J, Hedeen D, Zhu J, Capener J, Shaw D, et al.
PLoS Biol
. 2021 Apr;
19(4):e3001191.
PMID: 33886552
The Hedgehog (Hh) pathway is essential for organ development, homeostasis, and regeneration. Dysfunction of this cascade drives several cancers. To control expression of pathway target genes, the G protein-coupled receptor...
3.
Adolfi M, Herpin A, Martinez-Bengochea A, Kneitz S, Regensburger M, Grunwald D, et al.
Front Cell Dev Biol
. 2021 Feb;
8:613497.
PMID: 33537305
Sex determination (SD) is a highly diverse and complex mechanism. In vertebrates, one of the first morphological differences between the sexes is the timing of initiation of the first meiosis,...
4.
Teerlink C, Jurynec M, Hernandez R, Stevens J, Hughes D, Brunker C, et al.
Ann Hum Genet
. 2020 Oct;
85(2):58-72.
PMID: 33026655
Osteoporosis is a common skeletal disorder characterized by deterioration of bone tissue. The set of genetic factors contributing to osteoporosis is not completely specified. High-risk osteoporosis pedigrees were analyzed to...
5.
Chagovetz A, Shaw D, Ritchie E, Hoshijima K, Grunwald D
Dis Model Mech
. 2019 Aug;
13(2).
PMID: 31383689
Mutations affecting ryanodine receptor (RyR) calcium release channels commonly underlie congenital myopathies. Although these channels are known principally for their essential roles in muscle contractility, mutations in the human gene...
6.
Morrow Z, Maxwell A, Hoshijima K, Talbot J, Grunwald D, Amacher S
Dev Dyn
. 2017 Jul;
246(10):759-769.
PMID: 28691257
Background: T-box genes encode a large transcription factor family implicated in many aspects of development. We are focusing on two related zebrafish T-box genes, tbx6l and tbx16, that are expressed...
7.
Beumer K, Trautman J, Christian M, Dahlem T, Lake C, Hawley R, et al.
G3 (Bethesda)
. 2013 Aug;
3(10):1717-25.
PMID: 23979928
Zinc-finger nucleases have proven to be successful as reagents for targeted genome manipulation in Drosophila melanogaster and many other organisms. Their utility has been limited, however, by the significant failure...
8.
Ota S, Hisano Y, Muraki M, Hoshijima K, Dahlem T, Grunwald D, et al.
Genes Cells
. 2013 Apr;
18(6):450-8.
PMID: 23573916
The heteroduplex mobility assay (HMA) is widely used to characterize strain variants of human viruses. To determine whether it can detect small sequence differences in homologous templates, we constructed a...
9.
Wang X, Kopinke D, Lin J, McPherson A, Duncan R, Otsuna H, et al.
Dev Cell
. 2012 Sep;
23(3):624-36.
PMID: 22975330
Previous studies have raised the possibility that Wnt signaling may regulate both neural progenitor maintenance and neuronal differentiation within a single population. Here we investigate the role of Wnt/β-catenin activity...
10.
Xing L, Hoshijima K, Grunwald D, Fujimoto E, Quist T, Sneddon J, et al.
PLoS One
. 2012 Sep;
7(8):e43968.
PMID: 22937139
foxP2, a forkhead-domain transcription factor, is critical for speech and language development in humans, but its role in the establishment of CNS connectivity is unclear. While in vitro studies have...