David J Farrell
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Explore the profile of David J Farrell including associated specialties, affiliations and a list of published articles.
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173
Citations
3357
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Recent Articles
11.
Flamm R, Rhomberg P, Farrell D, Jones R
Diagn Microbiol Infect Dis
. 2016 Jun;
86(1):66-9.
PMID: 27352729
Pexiganan, in Phase 3 clinical development for topical use, exhibited bactericidal activity in vitro against Gram-positive and -negative isolates and was also shown to have a low potential for resistance...
12.
Sader H, Castanheira M, Farrell D, Flamm R, Mendes R, Jones R
Int J Antimicrob Agents
. 2016 Jun;
48(2):144-50.
PMID: 27291285
Bacterial organisms (n = 13,494) were consecutively collected in 2011-2014 from 21 Latin American medical centres (11 nations). Antimicrobial susceptibility was determined by broth microdilution at a central laboratory. Tigecycline...
13.
Huband M, Castanheira M, Farrell D, Flamm R, Jones R, Sader H, et al.
Int J Antimicrob Agents
. 2016 May;
47(6):495-9.
PMID: 27211209
The in vitro activity of dalbavancin was evaluated against 9303 Staphylococcus aureus and 2670 streptococci, including multidrug-resistant (MDR) isolates, collected from hospitalised patients in Europe and surrounding regions from 2011...
14.
Mendes R, Farrell D, Flamm R, Talbot G, Ivezic-Schoenfeld Z, Paukner S, et al.
Antimicrob Agents Chemother
. 2016 May;
60(7):4407-11.
PMID: 27161634
Lefamulin was evaluated against various Streptococcus pneumoniae serotypes that were collected from adults with lower respiratory tract infections. Lefamulin exhibited MIC50 and MIC90 values of 0.12 and 0.25 μg/ml, respectively,...
15.
Cannavino C, Mendes R, Sader H, Farrell D, Critchley I, Biek D, et al.
Pediatr Infect Dis J
. 2016 Apr;
35(7):813-5.
PMID: 27093165
Ceftaroline is the first β-lactam antibiotic with activity against methicillin-resistant Staphylococcus aureus (MRSA). We describe a ceftaroline-resistant MRSA strain, isolated from a girl with cystic fibrosis after 22 ceftaroline treatment...
16.
Farrell D, Flamm R, Sader H, Jones R
Antimicrob Agents Chemother
. 2016 Apr;
60(6):3662-8.
PMID: 27044551
Solithromycin, a fourth-generation macrolide (a fluoroketolide with enhanced activity against macrolide-resistant bacteria due to interaction with three ribosomal sites) and the first fluoroketolide, was tested against a 2014 collection of...
17.
Farrell D, Mendes R, Castanheira M, Jones R
Antimicrob Agents Chemother
. 2016 Mar;
60(6):3827-31.
PMID: 27021326
Fusidic acid (FA) activity was evaluated against 2,002 clinical staphylococcal isolates collected in U.S. hospitals during 2014. FA (MIC50/90, 0.12/0.12 μg/ml) inhibited 99.8% of Staphylococcus aureus isolates at ≤1 μg/ml....
18.
Mendes R, Watters A, Rhomberg P, Farrell D, Jones R
J Clin Microbiol
. 2016 Mar;
54(6):1668-1669.
PMID: 27008881
No abstract available.
19.
Mendes R, Farrell D, Sader H, Flamm R, Jones R
Antimicrob Agents Chemother
. 2016 Mar;
60(6):3817-20.
PMID: 27001823
Oritavancin (MIC50/90, 0.03/0.06 to 0.12 μg/ml) had potent activity against linezolid-resistant staphylococci, as well as Enterococcus faecalis and Enterococcus faecium (oritavancin MIC50/90, 0.015/0.12 μg/ml against both species). All linezolid-resistant isolates...
20.
Sader H, Farrell D, Flamm R, Jones R
Surg Infect (Larchmt)
. 2016 Mar;
17(4):443-7.
PMID: 26990170
Background: Ceftaroline fosamil is a novel cephalosporin approved by the United States Food and Drug Administration (US FDA) for treatment of acute bacterial skin and skin structure infection, including those...