David I Friedman
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Explore the profile of David I Friedman including associated specialties, affiliations and a list of published articles.
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20
Citations
868
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Recent Articles
1.
Xiao R, Chun L, Ronan E, Friedman D, Liu J, Xu X
Cell Rep
. 2015 May;
11(7):1123-33.
PMID: 25959815
Diet affects nearly every aspect of animal life such as development, metabolism, behavior, and aging, both directly by supplying nutrients and indirectly through gut microbiota. C. elegans feeds on bacteria,...
2.
Tyler J, Beeri K, Reynolds J, Alteri C, Skinner K, Friedman J, et al.
PLoS Pathog
. 2013 Apr;
9(3):e1003236.
PMID: 23555250
Enterohemorrhagic Escherichia coli (EHEC), particularly serotype O157:H7, causes hemorrhagic colitis, hemolytic uremic syndrome, and even death. In vitro studies showed that Shiga toxin 2 (Stx2), the primary virulence factor expressed...
3.
Bubunenko M, Court D, Al Refaii A, Saxena S, Korepanov A, Friedman D, et al.
Mol Microbiol
. 2012 Nov;
87(2):382-93.
PMID: 23190053
Escherichia coli NusA and NusB proteins bind specific sites, such as those in the leader and spacer sequences that flank the 16S region of the ribosomal RNA transcript, forming a...
4.
Fang G, Munera D, Friedman D, Mandlik A, Chao M, Banerjee O, et al.
Nat Biotechnol
. 2012 Nov;
30(12):1232-9.
PMID: 23138224
Single-molecule real-time (SMRT) DNA sequencing allows the systematic detection of chemical modifications such as methylation but has not previously been applied on a genome-wide scale. We used this approach to...
5.
Friedman D, Mozola C, Beeri K, Ko C, Reynolds J
Mol Microbiol
. 2011 Oct;
82(3):567-77.
PMID: 21985444
Bacteria in their struggle for survival have evolved or acquired defences against attacking phage. However, phage often contribute to this defence through mechanisms in which a prophage protects the bacterial...
6.
Livny J, LaRock C, Friedman D
Methods Mol Biol
. 2008 Dec;
501:253-65.
PMID: 19066826
The fate of lysogens following prophage induction has assumed added significance with the finding that in many pathogens virulence genes are carried on prophages and, in some, the production and/or...
7.
Eaton K, Friedman D, Francis G, Tyler J, Young V, Haeger J, et al.
Infect Immun
. 2008 Apr;
76(7):3054-63.
PMID: 18443087
Enterohemorrhagic Escherichia coli (EHEC) is a food-borne pathogen that causes hemorrhagic colitis and acute renal failure. We used a germ-free mouse model to investigate the role of host factors, Shiga...
8.
Adhya S, Court D, Friedman D, Gottesman M
Mol Microbiol
. 2008 Feb;
67(4):685-6.
PMID: 18237367
No abstract available.
9.
Zhou Y, Shi T, Mozola M, Olson E, Henthorn K, Brown S, et al.
J Bacteriol
. 2006 Mar;
188(6):2222-32.
PMID: 16513752
The N protein of phage lambda acts with Escherichia coli Nus proteins at RNA sites, NUT, to modify RNA polymerase (RNAP) to a form that overrides transcription terminators. These interactions...
10.
Friedman D, Forti R, Wall S, Crain E
Pediatr Emerg Care
. 2005 Aug;
21(8):487-92.
PMID: 16096591
Objective: The purpose of the study was to determine if bedside ultrasound (US) and perception of wound foreign bodies (FBs) are useful screening tools for detecting wound FBs in children....