David H Persing
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Explore the profile of David H Persing including associated specialties, affiliations and a list of published articles.
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64
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3839
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Recent Articles
1.
Rakeman-Cagno J, Persing D, Loeffelholz M
Expert Rev Mol Diagn
. 2023 Sep;
24(3):147-151.
PMID: 37724428
Introduction: Testing at the point of care (we also refer to the 'point of need'), with rapid, actionable results reported to the patient and provider within hours can impact the...
2.
Chen X, Li R, Ge S, Li Y, Cai C, Weng T, et al.
J Clin Microbiol
. 2023 May;
61(6):e0183222.
PMID: 37249422
The Xpert MTB/XDR assay met the critical need for etiologic diagnosis of tuberculosis and rifampin resistance in previous studies. However, its benefits in tailoring the treatment regimen and improving the...
3.
Atallah J, Ghebremichael M, Timmer K, Warren H, Mallinger E, Wallace E, et al.
Diagnostics (Basel)
. 2023 Mar;
13(5).
PMID: 36900096
Fever is a common presentation to urgent-care services and is linked to multiple disease processes. To rapidly determine the etiology of fever, improved diagnostic modalities are necessary. This prospective study...
4.
Schmitz J, Stratton C, Persing D, Tang Y
J Clin Microbiol
. 2022 Jul;
60(10):e0244621.
PMID: 35852340
Nearly 40 years have elapsed since the invention of the PCR, with its extremely sensitive and specific ability to detect nucleic acids via enzyme-mediated amplification. In turn, more than 2...
5.
Verma R, Patil S, Zhang N, Moreira F, Vitorio M, Santos A, et al.
Am J Respir Crit Care Med
. 2021 Aug;
204(11):1317-1326.
PMID: 34375564
Standardized dosing of antitubercular drugs contributes to a substantial incidence of toxicities, inadequate treatment response, and relapse, in part due to variable drug concentrations achieved. SNPs in the (-acetyltransferase-2) gene...
6.
Zimmer A, Schumacher S, Sodersten E, Mantsoki A, Wyss R, Persing D, et al.
BMC Res Notes
. 2021 Jul;
14(1):247.
PMID: 34193258
Objectives: A novel 3-gene host transcriptional signature (GBP5, DUSP3 and KLF2) has been validated for tuberculosis (TB) treatment monitoring using laboratory-based RNA sequencing platforms. The signature was recently translated by...
7.
Moreira F, Verma R, Pereira Dos Santos P, Leite A, da Silva Santos A, Pivetta de Araujo R, et al.
EClinicalMedicine
. 2021 Apr;
33:100776.
PMID: 33842866
Background: There is a need to identify scalable tuberculosis screening strategies among high burden populations. The WHO has identified a non-sputum-based triage test as a development priority. Methods: We performed...
8.
Mostafa H, Carroll K, Hicken R, Berry G, Manji R, Smith E, et al.
J Clin Microbiol
. 2020 Dec;
59(3).
PMID: 33298613
With the approach of respiratory virus season in the Northern Hemisphere, clinical microbiology and public health laboratories will need rapid diagnostic assays to distinguish severe acute respiratory syndrome coronavirus 2...
9.
Sodersten E, Ongarello S, Mantsoki A, Wyss R, Persing D, Banderby S, et al.
J Clin Microbiol
. 2020 Dec;
59(3).
PMID: 33298607
A nonsputum triage test to rule out tuberculosis (TB) disease is a WHO high-priority diagnostic, and a combinatory score based on a 3-gene host signature has shown promise in discriminating...
10.
Li H, Sun K, Persing D, Tang Y, Shen D
Clin Infect Dis
. 2020 Sep;
73(2):318-320.
PMID: 32997114
A 10:1 pooled test strategy on-site at an airport of China was pursued, resulting in increased test throughput, limited use of reagents, and increased testing efficiency without loss of sensitivity....