David Guenat
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Explore the profile of David Guenat including associated specialties, affiliations and a list of published articles.
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20
Citations
193
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Recent Articles
1.
Debernardi A, Meurisse A, Pretet J, Guenat D, Monnien F, Spehner L, et al.
Front Oncol
. 2022 Oct;
12:941676.
PMID: 36313663
Squamous Cell Carcinoma of the Anal canal (SCCA) is a rare disease associated with a Human Papillomavirus (HPV) infection in most cases, predominantly the HPV16 genotype. About 15% of SCCA...
2.
Debernardi A, Valot B, Almarcha J, Guenat D, Hocquet D, Algros M, et al.
J Med Virol
. 2022 Jul;
94(11):5512-5518.
PMID: 35799409
Human papillomavirus (HPV) 16 exhibits different variants that may differ in their carcinogenic risk. To identify some high-risk variants, we sequenced and compared HPV16 whole genomes obtained from a longitudinal...
3.
Molimard C, LHuillier V, Overs A, Soret C, Algros M, Mougin C, et al.
J Int Med Res
. 2021 Jul;
49(7):3000605211022534.
PMID: 34232797
Objectives: Human papillomavirus (HPV) is a risk factor for head and neck squamous cell carcinoma (HNSCC), which is currently increasing worldwide. We evaluated the prevalence of HPV DNA and p16...
4.
Beziat V, Rapaport F, Hu J, Titeux M, Bonnet des Claustres M, Bourgey M, et al.
Cell
. 2021 Jul;
184(14):3812-3828.e30.
PMID: 34214472
We study a patient with the human papilloma virus (HPV)-2-driven "tree-man" phenotype and two relatives with unusually severe HPV4-driven warts. The giant horns form an HPV-2-driven multifocal benign epithelial tumor...
5.
Jacquin E, Guenat D, Riethmuller D, Mougin C, Pretet J
Virologie (Montrouge)
. 2020 Oct;
18(4):211-228.
PMID: 33065933
High-risk human Papillomaviruses (HR-HPV) - the most carcinogenic infectious agents - are responsible for the development of cervical cancer. The knowledge of HPV infection natural history and viral carcinogenesis led...
6.
Perrard J, Morel A, Meznad K, Paget-Bailly P, Dalstein V, Guenat D, et al.
Oncol Lett
. 2020 Jan;
19(1):1074-1081.
PMID: 31897221
HPV16 is the most carcinogenic human papillomavirus and causes >50% of cervical cancers, the majority of anal cancers and 30% of oropharyngeal squamous cell carcinomas. HPV carcinogenesis relies on the...
7.
Bernard-Tessier A, Jeannot E, Guenat D, Debernardi A, Michel M, Proudhon C, et al.
Clin Cancer Res
. 2018 Dec;
25(7):2109-2115.
PMID: 30504426
Purpose: Human papillomavirus (HPV) is found in 90% of squamous cell carcinomas of the anal canal (SCCA). We investigated the clinical validity of HPV circulating tumor DNA (ctDNA) detection in...
8.
Vrecko S, Guenat D, Mercier-Letondal P, Faucheu H, Dosset M, Royer B, et al.
Oncotarget
. 2018 Nov;
9(83):35394-35407.
PMID: 30459932
Sorafenib, a multi-targeted kinase inhibitor, is the current standard systemic treatment for advanced hepatocellular carcinoma. Sorafenib has anti-angiogenic and anti-proliferative properties and is also known to favor anti-tumor T cell...
9.
Guenat D, Dalstein V, Mauny F, Saunier M, Briolat J, Clavel C, et al.
Papillomavirus Res
. 2018 Oct;
6:27-32.
PMID: 30343011
High risk HPV infection is the necessary cause for the development of precancerous and cancerous lesions of the cervix. Among HPV, HPV16 represents the most carcinogenic type. Since the determination...
10.
Belglaiaa E, Souho T, Badaoui L, Segondy M, Pretet J, Guenat D, et al.
BMJ Open
. 2018 Aug;
8(8):e020343.
PMID: 30139893
Objective: To explore awareness about cervical cancer among Moroccan women attending an HIV treatment centre in Laâyoune city, Morocco. Design: A cross-sectional study was conducted from April to June 2017...