David Goodale
Overview
Explore the profile of David Goodale including associated specialties, affiliations and a list of published articles.
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20
Citations
508
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Recent Articles
1.
Bhat V, Piaseczny M, Goodale D, Patel U, Sadri A, Allan A
Clin Exp Metastasis
. 2024 Apr;
41(5):717-731.
PMID: 38581619
Patients with triple-negative breast cancer (TNBC) have an increased propensity to develop lung metastasis. Our previous studies demonstrated that stem-like ALDHCD44 breast cancer cells interact with lung-derived soluble factors, resulting...
2.
Khan S, Xia Y, Goodale D, Schoettle G, Allan A
Biomedicines
. 2021 Nov;
9(11).
PMID: 34829810
The lung is one of the deadliest sites of breast cancer metastasis, particularly for triple negative breast cancer (TNBC). We have previously shown that the lung produces several soluble factors...
3.
Wang T, Chen Y, Goodale D, Allan A, Ronald J
Mol Ther Oncolytics
. 2021 Mar;
20:209-219.
PMID: 33665359
Gene vectors regulated by tumor-specific promoters to express transgenes specifically in cancer cells are an emerging approach for cancer diagnosis and treatment. Minicircles are shortened plasmids stripped of prokaryotic sequences...
4.
Kitz J, Goodale D, Postenka C, Lowes L, Allan A
Clin Exp Metastasis
. 2021 Jan;
38(1):97-108.
PMID: 33415568
Circulating tumor cells (CTCs) present an opportunity to detect/monitor metastasis throughout disease progression. The CellSearch® is currently the only FDA-approved technology for CTC detection in patients. The main limitation of...
5.
Bhat V, Lefebvre C, Goodale D, Rodriguez-Torres M, Allan A
J Vis Exp
. 2020 Oct;
(164).
PMID: 33074254
Breast cancer stem cells (BCSCs) are cancer cells with inherited or acquired stem cell-like characteristics. Despite their low frequency, they are major contributors to breast cancer initiation, relapse, metastasis and...
6.
Medeiros B, Goodale D, Postenka C, Lowes L, Kiser P, Hearn S, et al.
Cancers (Basel)
. 2020 Jan;
12(1).
PMID: 31936750
The lung is one of the deadliest sites of breast cancer metastasis, particularly in patients with triple-negative (TN) disease. We hypothesized that the presence of a TN primary breast tumor...
7.
Ragab D, Sabra S, Xia Y, Goodale D, Allan A, Rohani S
J Pharm Sci
. 2019 Jul;
108(11):3528-3539.
PMID: 31351864
Spheroidal microparticles versatility as a drug carrier makes it a real workhorse in drug delivery applications. Despite of their long history, few research publications emphasize on how to improve their...
8.
Sabra S, Sheweita S, Haroun M, Ragab D, Eldemellawy M, Xia Y, et al.
J Pharm Sci
. 2018 Dec;
108(5):1713-1725.
PMID: 30528944
Magnetic nanocarriers are useful in targeted cancer therapy. Dasatinib (DAS)-loaded magnetic micelles were prepared for magnetically guided drug delivery. The magnetic nanoplatform is composed of hydrophobic oleic acid-coated magnetite (FeO)...
9.
Kitz J, Lowes L, Goodale D, Allan A
Diagnostics (Basel)
. 2018 May;
8(2).
PMID: 29710776
The majority of cancer deaths occur because of metastasis since current therapies are largely non-curative in the metastatic setting. The use of in vivo preclinical mouse models for assessing metastasis...
10.
Sabra S, Elzoghby A, Sheweita S, Haroun M, Helmy M, Eldemellawy M, et al.
Eur J Pharm Biopharm
. 2018 Apr;
128:156-169.
PMID: 29689288
Protein-based micelles have shown significant potential for tumor-targeted delivery of anti-cancer drugs. In this light, self-assembled nanocarriers based on GRAS (Generally recognized as safe) amphiphilic protein co-polymers were synthesized via...