Carl O Postenka
Overview
Explore the profile of Carl O Postenka including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
647
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0
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Recent Articles
1.
Krstic M, Hassan H, Kolendowski B, Hague M, Anborgh P, Postenka C, et al.
Lab Invest
. 2019 Oct;
100(3):400-413.
PMID: 31570773
TBX3 is a member of the highly conserved family of T-box transcription factors involved in embryogenesis, organogenesis and tumor progression. While the functional role of TBX3 in tumorigenesis has been...
2.
Krstic M, Kolendowski B, Cecchini M, Postenka C, Hassan H, Andrews J, et al.
J Pathol
. 2019 Jan;
248(2):191-203.
PMID: 30697731
The acquisition of cellular invasiveness by breast epithelial cells and subsequent transition from ductal carcinoma in situ (DCIS) to invasive breast cancer is a critical step in breast cancer progression....
3.
Krstic M, MacMillan C, Leong H, Clifford A, Souter L, Dales D, et al.
BMC Cancer
. 2016 Aug;
16(1):671.
PMID: 27553211
Background: TBX3 is a T-box transcription factor repressor that is elevated in metastatic breast cancer and is believed to promote malignancy of tumor cells, possibly by promoting cell survival and...
4.
Sonke E, Verrydt M, Postenka C, Pardhan S, Willie C, Mazzola C, et al.
Nitric Oxide
. 2015 Jun;
49:26-39.
PMID: 26068241
Clear cell renal cell carcinoma (ccRCC) is characterized by Von Hippel-Lindau (VHL)-deficiency, resulting in pseudohypoxic, angiogenic and glycolytic tumours. Hydrogen sulfide (H2S) is an endogenously-produced gasotransmitter that accumulates under hypoxia...
5.
Leong H, Robertson A, Stoletov K, Leith S, Chin C, Chien A, et al.
Cell Rep
. 2014 Sep;
8(5):1558-70.
PMID: 25176655
Tumor cell extravasation is a key step during cancer metastasis, yet the precise mechanisms that regulate this dynamic process are unclear. We utilized a high-resolution time-lapse intravital imaging approach to...
6.
Bramwell V, Tuck A, Chapman J, Anborgh P, Postenka C, Al-Katib W, et al.
Breast Cancer Res
. 2014 Jan;
16(1):R8.
PMID: 24451146
Introduction: Osteopontin (OPN) is a malignancy-associated glycoprotein that contributes functionally to tumor aggressiveness. In metastatic breast cancer, we previously demonstrated that elevated OPN in primary tumor and blood was associated...
7.
Goulet B, Kennette W, Ablack A, Postenka C, Hague M, Mymryk J, et al.
Lab Invest
. 2011 Apr;
91(8):1181-7.
PMID: 21502940
Maspin (mammary serine protease inhibitor or SerpinB5) acts as a tumor suppressor when overexpressed in aggressive cancer cell lines. However, its role in human cancer is controversial. Maspin expression has...
8.
Beausoleil M, Schulze E, Goodale D, Postenka C, Allan A
BMC Cancer
. 2011 Jan;
11:25.
PMID: 21247495
Background: Osteopontin (OPN) is a secreted phosphoprotein often overexpressed at high levels in the blood and primary tumors of breast cancer patients. OPN contains two integrin-binding sites and a thrombin...
9.
Souter L, Andrews J, Zhang G, Cook A, Postenka C, Al-Katib W, et al.
Lab Invest
. 2010 May;
90(8):1247-58.
PMID: 20458274
Early breast cancer progression involves advancement through specific morphological stages including atypical ductal hyperplasia (ADH), ductal carcinoma in situ (DCIS) and invasive mammary carcinoma (IMC), although not necessarily always in...
10.
Goodale D, Phay C, Postenka C, Keeney M, Allan A
Cytometry A
. 2008 Oct;
75(4):344-55.
PMID: 18855920
The inability to sensitively detect metastatic cells in preclinical models of cancer has created challenges for studying metastasis in experimental systems. We previously developed a flow cytometry (FCM) method for...