David Garcia-Dorado
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Explore the profile of David Garcia-Dorado including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Zhang Y, Garcia-Gabilondo M, Grayston A, Feiner I, Anton-Sales I, Loiola R, et al.
Nanoscale
. 2020 Feb;
12(8):4988-5002.
PMID: 32057060
Designing theranostic nanocarriers with high protein payload and multimodality tracking without cross interferences between the different imaging probes and the delicate protein cargo is challenging. Here, chemical modifications of poly(lactic-co-glycolic...
12.
Simo R, Baneras J, Hernandez C, Rodriguez-Palomares J, Valente F, Gutierrez L, et al.
BMJ Open Diabetes Res Care
. 2020 Jan;
7(1):e000845.
PMID: 31908800
Objective: Detection of subclinical cardiovascular disease (CVD) has significant impact on the management of type 2 diabetes. We examined whether the assessment of diabetic retinopathy (DR) is useful for identifying...
13.
Rossello X, Rodriguez-Sinovas A, Vilahur G, Crisostomo V, Jorge I, Zaragoza C, et al.
Sci Rep
. 2020 Jan;
9(1):20290.
PMID: 31889088
Despite many cardioprotective interventions have shown to protect the heart against ischemia/reperfusion injury in the experimental setting, only few of them have succeeded in translating their findings into positive proof-of-concept...
14.
Ruiz-Meana M, Boengler K, Garcia-Dorado D, Hausenloy D, Kaambre T, Kararigas G, et al.
Br J Pharmacol
. 2019 Dec;
177(23):5270-5286.
PMID: 31863453
Translation of cardioprotective interventions aimed at reducing myocardial injury during ischaemia-reperfusion from experimental studies to clinical practice is an important yet unmet need in cardiovascular medicine. One particular challenge facing...
15.
Importance of infarct size versus other variables for clinical outcomes after PPCI in STEMI patients
Bochaton T, Claeys M, Garcia-Dorado D, Mewton N, Bergerot C, Jossan C, et al.
Basic Res Cardiol
. 2019 Dec;
115(1):4.
PMID: 31832789
Despite promising experimental studies and encouraging proof-of-concept clinical trials, interventions aimed at limiting infarct size have failed to improve clinical outcomes in patients with ST-elevation myocardial infarction (STEMI). Our objective...
16.
Diez E, Sanchez J, Prado N, Ponce Zumino A, Garcia-Dorado D, Miatello R, et al.
Int J Mol Sci
. 2019 Nov;
20(23).
PMID: 31775376
Ischemic postconditioning (IPoC) reduces reperfusion arrhythmias but the antiarrhythmic mechanisms remain unknown. The aim of this study was to analyze IPoC electrophysiological effects and the role played by adenosine A,...
17.
Mila L, Barrabes J, Lidon R, Sambola A, Baneras J, Oristrell G, et al.
Rev Esp Cardiol (Engl Ed)
. 2019 Nov;
73(5):376-382.
PMID: 31706709
Introduction And Objectives: Optimal lipid control is difficult to attain. We assessed preadmission achievement of the European Society of Cardiology targets for low-density lipoprotein-cholesterol (LDL-C) control in patients admitted for...
18.
Penela P, Inserte J, Ramos P, Rodriguez-Sinovas A, Garcia-Dorado D, Mayor Jr F
EBioMedicine
. 2019 Oct;
48:605-618.
PMID: 31594751
Background: Identification of signaling pathways altered at early stages after cardiac ischemia/reperfusion (I/R) is crucial to develop timely therapies aimed at reducing I/R injury. The expression of G protein-coupled receptor...
19.
Sambola A, Bueno H, Miranda B, Hernandez A, Limeres J, Garcia Del Blanco B, et al.
Cardiovasc Drugs Ther
. 2019 Jul;
33(4):425-433.
PMID: 31332653
Background: The impact of short or prolonged use of triple therapy (TT) on outcomes in patients with atrial fibrillation (AF) and high risk of bleeding undergoing percutaneous coronary intervention (PCI)...
20.
Ibanez B, Aletras A, Arai A, Arheden H, Bax J, Berry C, et al.
J Am Coll Cardiol
. 2019 Jul;
74(2):238-256.
PMID: 31296297
After a reperfused myocardial infarction (MI), dynamic tissue changes occur (edema, inflammation, microvascular obstruction, hemorrhage, cardiomyocyte necrosis, and ultimately replacement by fibrosis). The extension and magnitude of these changes contribute...