David G Jayne
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Explore the profile of David G Jayne including associated specialties, affiliations and a list of published articles.
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79
Citations
2599
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Recent Articles
1.
Chapman S, Ahmed S, Cave L, Morton K, Tiernan J, Limbert S, et al.
Colorectal Dis
. 2024 Nov;
PMID: 39497473
Aim: Recovery after surgery for colorectal cancer is a complex process, involving numerous physiological, emotional, social and economic challenges. Good information is a key factor for enabling patients to recover...
2.
Martinez J, Ingram N, Kapur N, Jayne D, Beales P
Pain Rep
. 2024 Oct;
9(6):e1196.
PMID: 39399306
Pain, a complex and debilitating condition, necessitates innovative therapeutic strategies to alleviate suffering and enhance patients' quality of life. Vesicular systems hold the potential to enhance precision of drug localisation...
3.
Chapman S, Kowal M, Helliwell J, Lockwood S, Naylor M, Croft J, et al.
Colorectal Dis
. 2024 Oct;
26(12):2101-2111.
PMID: 39394910
Aim: Ileus is characterized by a period of intestinal dysmotility after surgery, leading to vomiting and constipation. In preclinical models, vagus nerve stimulation reduces intestinal inflammation and prevents smooth muscle...
4.
Suresh N, Karanth R, Cheah R, Casey J, Jayne D, Del Galdo F
J Scleroderma Relat Disord
. 2024 Oct;
9(3):210-215.
PMID: 39386265
Systemic sclerosis is an autoimmune disorder which frequently affects the gastrointestinal tract. Anorectal dysfunction is common in systemic sclerosis and is manifested mainly by atrophy of internal anal sphincter. Faecal...
5.
Helliwell J, Jayne D
J Gastrointest Oncol
. 2024 Sep;
15(4):1993-1995.
PMID: 39279950
No abstract available.
6.
Naidu K, Chapuis P, Chan C, Rickard M, West N, Jayne D, et al.
World J Surg Oncol
. 2024 Aug;
22(1):216.
PMID: 39174976
Background: Ex vivo tissue morphometric (TM) measurements have been proposed as a quality marker for colorectal cancer (CRC) surgery. However, their survival associations require clarification. This study aimed to evaluate...
7.
Martinez J, Maisey T, Ingram N, Kapur N, Beales P, Jayne D
Surg Open Sci
. 2024 Jul;
20:106-115.
PMID: 39021615
Background: Postoperative pain following abdominal surgery is a significant obstacle to patient recovery, often necessitating high analgesic doses associated with adverse effects like cognitive impairment and cardiorespiratory depression. Reliable animal...
8.
Bolton W, Aruparayil N, Cundill B, McCulloch P, Gnanaraj J, Bundu I, et al.
BMJ Surg Interv Health Technol
. 2024 Jun;
6(1):e000248.
PMID: 38883696
Objective: The Global IDEAL Sub-Framework Study aimed to combine the intended effects of the 2009/2019 IDEAL (Idea, Development, Exploration, Assessment, Long-term study) Framework recommendations on evaluating surgical innovation with the...
9.
King A, Maisey T, Harris E, Poulter J, Jayne D, Khot M
Photochem Photobiol Sci
. 2024 Apr;
23(6):1067-1075.
PMID: 38625651
Photodynamic Therapy (PDT) is an emerging method to treat colorectal cancers (CRC). Hypericin (HYP) is an effective mediator of PDT and the ABCG2 inhibitor, Febuxostat (FBX) could augment PDT. HT29...
10.
Khaled Y, Khot M, Aiyappa-Maudsley R, Maisey T, Pramanik A, Tiernan J, et al.
Nanoscale
. 2024 Mar;
16(14):7185-7199.
PMID: 38506227
Theranostic nanoparticles hold promise for simultaneous imaging and therapy in colorectal cancer. Carcinoembryonic antigen can be used as a target for these nanoparticles because it is overexpressed in most colorectal...