David G Jayne
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Explore the profile of David G Jayne including associated specialties, affiliations and a list of published articles.
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79
Citations
2599
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Recent Articles
11.
Lintern N, Smith A, Jayne D, Khaled Y
Cancers (Basel)
. 2023 Aug;
15(16).
PMID: 37627163
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest solid malignancies, with a five-year survival of less than 10%. The resistance of the disease and the associated lack of therapeutic...
12.
Jolugbo P, Willott T, Lin W, Maisey T, OCallaghan D, Green M, et al.
Nanoscale
. 2023 Jul;
15(30):12476-12480.
PMID: 37466243
We developed a carcinoembryonic antigen (CEA) conjugated polymer nanoparticle (CPN510-CEA-Af) probe to target CEA-expressing CRC cells . Its efficacy was evaluated in 2D and 3D cultures of LS174T, LoVo, and...
13.
Downey C, Bainbridge J, Jayne D, Meads D
Br J Surg
. 2023 Jun;
110(9):1206-1212.
PMID: 37335925
Background: Postoperative complications are common, but there are limited data regarding their implications on patients' quality of life. This study aimed to address this gap in the literature by analysing...
14.
Bautista M, Kowal M, Cave D, Downey C, Jayne D
J Clin Transl Sci
. 2023 Jun;
7(1):e129.
PMID: 37313385
Contactless photoplethysmography (cPPG) is a method of physiological monitoring. It differs from conventional monitoring methods (e.g., saturation probe) by ensuring no contact with the subject by use of a camera....
15.
Corrigan N, Brown J, Emsley R, Jayne D, Walwyn R
Trials
. 2023 Apr;
24(1):294.
PMID: 37095568
Background: Surgical interventions are complex. Key elements of this complexity are the surgeon and their learning curve. They pose methodological challenges in the design, analysis and interpretation of surgical RCTs....
16.
Smith M, Khot M, Taccola S, Fry N, Muhonen P, Tipper J, et al.
Biomed Microdevices
. 2023 Apr;
25(2):16.
PMID: 37084116
This paper presents the engineering and validation of an enabling technology that facilitates new capabilities in in vitro cell models for high-throughput screening and tissue engineering applications. This is conducted...
17.
Helliwell J, Thompson J, Smart N, Jayne D, Chapman S
Health Sci Rep
. 2022 May;
5(3):e541.
PMID: 35509384
Objectives: This study examines the conduct of systematic reviews during the early stages of the COVID-19 pandemic, including compliance to protocol registration and duplication of reviews on similar topics. The...
18.
Kitchen W, Downey C, Brown J, Jayne D, Randell R
Surg Innov
. 2022 Apr;
29(6):804-810.
PMID: 35451350
Background: Medical technologies have the potential to improve quality and efficiency of healthcare. The design of clinical trials should consider participants' perspectives to optimise enrolment, engagement and satisfaction. This study...
19.
Kim W, Khot M, Woo H, Hong S, Baek D, Maisey T, et al.
Nat Commun
. 2022 Apr;
13(1):2178.
PMID: 35449140
Photodynamic therapy (PDT) offers several advantages for treating cancers, but its efficacy is highly dependent on light delivery to activate a photosensitizer. Advances in wireless technologies enable remote delivery of...
20.
Armstrong G, Khot M, Portal C, West N, Perry S, Maisey T, et al.
Surg Oncol
. 2021 Nov;
40:101679.
PMID: 34839199
Background: The c-Met protein is overexpressed in many gastrointestinal cancers. We explored EMI-137, a novel c-Met targeting fluorescent probe, for application in fluorescence-guided colon surgery, in HT-29 colorectal cancer (CRC)...