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David Frommhold

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Citations 704
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Recent Articles
1.
Immler R, Nussbaumer K, Doerner A, El Bounkari O, Huber S, Abisch J, et al.
Proc Natl Acad Sci U S A . 2024 Apr; 121(19):e2319057121. PMID: 38687790
Eosinophil recruitment is a pathological hallmark of many allergic and helminthic diseases. Here, we investigated chemokine receptor CCR3-induced eosinophil recruitment in sialyltransferase mice. We found a marked decrease in eosinophil...
2.
Lajqi T, Kostlin-Gille N, Bauer R, Zarogiannis S, Lajqi E, Ajeti V, et al.
Biomedicines . 2023 Mar; 11(3). PMID: 36979747
For almost nearly a century, memory functions have been attributed only to acquired immune cells. Lately, this paradigm has been challenged by an increasing number of studies revealing that innate...
3.
Lajqi T, Frommhold D, Braun M, Alexander Kranig S, Poschl J, Hudalla H
Cell Immunol . 2022 May; 376:104535. PMID: 35537323
Neutrophils primarily act as first responders in acute infection and directly maintain inflammatory responses. However, a growing body of evidence suggests that neutrophils also bear the potential to mediate chronic...
4.
Lajqi T, Kostlin-Gille N, Hillmer S, Braun M, Kranig S, Dietz S, et al.
Biomedicines . 2022 Feb; 10(2). PMID: 35203650
Neutrophils are classically characterized as merely reactive innate effector cells. However, the microbiome is known to shape the education and maturation process of neutrophils, improving their function and immune-plasticity. Recent...
5.
Lajqi T, Braun M, Alexander Kranig S, Frommhold D, Poschl J, Hudalla H
Int J Mol Sci . 2021 Sep; 22(18). PMID: 34575963
A growing body of evidence suggests that innate immune cells can respond in a memory-like (adaptive) fashion, which is referred to as trained immunity. Only few in vivo studies have...
6.
Lajqi T, Poschl J, Frommhold D, Hudalla H
Front Immunol . 2020 Nov; 11:568685. PMID: 33133082
Newborns are highly susceptible to infections and mainly rely on innate immune functions. Reduced reactivity, delayed activation and subsequent failure to resolve inflammation however makes the neonatal immune system a...
7.
Meyburg J, Frommhold D, Motsch J, Kuss N
J Intensive Care Med . 2020 Sep; 36(11):1305-1312. PMID: 32938279
Objectives: To describe safety and feasibility of long-term inhalative sedation (LTIS) in children with severe respiratory diseases compared to patients with normal lung function with respect to recent studies that...
8.
Fitterer R, Lajqi T, Alexander Kranig S, Braun M, Theissig N, Kuss N, et al.
J Clin Med . 2020 Sep; 9(9). PMID: 32867030
(1) Background: L-arginine is a complex modulator of immune functions, and its levels are known to decrease under septic conditions. L-arginine may suppress leukocyte recruitment in vivo; however, little is...
9.
Marissen J, Haiss A, Meyer C, Van Rossum T, Bunte L, Frommhold D, et al.
BMJ Open . 2019 Nov; 9(11):e032617. PMID: 31753895
Introduction: The healthy 'eubiosis' microbiome in infancy is regarded as the microbiome derived from term, vaginally delivered, antibiotic free, breastfed infants at 4-6 months. Dysbiosis is regarded as a deviation...
10.
Alexander Kranig S, Tschada R, Braun M, Poschl J, Frommhold D, Hudalla H
Pediatr Res . 2019 Nov; 87(4):798. PMID: 31683276
No abstract available.