David Frommhold
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Explore the profile of David Frommhold including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Alexander Kranig S, Tschada R, Braun M, Patry C, Poschl J, Frommhold D, et al.
Pediatr Res
. 2019 May;
86(2):188-194.
PMID: 31091530
Background: A growing body of evidence defines inflammation as a hallmark feature of disease pathogenesis of Duchenne muscular dystrophy. To tailor potential immune modulatory interventions, a better understanding of immune...
12.
Hudalla H, Karenberg K, Kuon R, Poschl J, Tschada R, Frommhold D
Pediatr Res
. 2018 Aug;
84(5):757-764.
PMID: 30135596
Background: A pro-inflammatory intrauterine milieu accounts for increased perinatal morbidity and mortality. We asked how maternal inflammation as seen in endotoxemia affects fetal leukocyte recruitment in vivo during late gestation....
13.
Hartel C, Pagel J, Spiegler J, Buma J, Henneke P, Zemlin M, et al.
Sci Rep
. 2017 Jul;
7(1):5633.
PMID: 28717131
We performed an observational study with very-low-birth weight infants (VLBWI) ≤33 weeks of gestation born in centers of the German Neonatal Network (GNN; (total n = 8534, n = 6229...
14.
Karenberg K, Hudalla H, Frommhold D
Mol Cell Pediatr
. 2016 Oct;
3(1):35.
PMID: 27778308
Impaired cellular innate immune defense accounts for susceptibility to sepsis and its high morbidity and mortality in preterm infants. Leukocyte recruitment is an integral part of the cellular immune response...
15.
Buschmann K, Poeschl J, Braach N, Hudalla H, Kuss N, Frommhold D
Mediators Inflamm
. 2015 Mar;
2015:757059.
PMID: 25767334
Although fish oil-based and olive oil-based lipid emulsions have been shown to exert anti-inflammatory functions, the immunomodulating properties of lipids are still controversial. Therefore, we investigated the anti-inflammatory effect of...
16.
Koch L, Frommhold D, Buschmann K, Kuss N, Poeschl J, Ruef P
Mediators Inflamm
. 2014 Dec;
2014:283126.
PMID: 25530682
As nuclear factor kappa B (NF-κB) and mitogen-activated protein kinases (MAPKs) seem to be critical mediators in the inflammatory response, we studied the effects of lipopolysaccharide (LPS) and lipoteichoic acid...
17.
Buschmann K, Tschada R, Metzger M, Braach N, Kuss N, Hudalla H, et al.
BMC Immunol
. 2014 Nov;
15:53.
PMID: 25428166
Background: Insufficient leukocyte recruitment may be one reason for the high incidence of life-threatening infections in preterm infants. Since the receptor of advanced glycation end products (RAGE) is a known...
18.
Ronellenfitsch S, Tabatabai J, Bottcher S, Diedrich S, Frommhold D, Schubert-Bast S, et al.
J Med Case Rep
. 2014 Jun;
8:164.
PMID: 24885145
Introduction: Enteroviruses commonly encounter babies and children and infections present in a wide variety of symptoms ranging from asymptomatic infection, benign illness, and aseptic meningitis, hand-foot-and-mouth disease to severe life-threatening...
19.
Braach N, Buschmann K, Pflaum J, Hudalla H, Koch L, Ryschich E, et al.
Mediators Inflamm
. 2014 May;
2014:743678.
PMID: 24876676
By binding β 2-integrins both ICAM-1 and the receptor for advanced glycation end products (RAGE) mediate leukocyte recruitment in a stimulus-dependent manner. Using different inflammatory mouse models we investigated how...
20.
Braach N, Frommhold D, Buschmann K, Pflaum J, Koch L, Hudalla H, et al.
PLoS One
. 2014 Mar;
9(2):e89422.
PMID: 24586767
Aims: The receptor for advanced glycation endproducts, RAGE, is a multiligand receptor and NF-κB activator leading to perpetuation of inflammation. We investigated whether and how RAGE is involved in mediation...