David E Whitworth
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Explore the profile of David E Whitworth including associated specialties, affiliations and a list of published articles.
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66
Citations
1070
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Recent Articles
1.
Arakal B, Rowlands R, Maddocks S, Whitworth D, James P, Livingstone P
J Appl Microbiol
. 2024 Dec;
136(1.
PMID: 39730144
Aims: Myxobacteria are non-pathogenic, saprophytic, soil-dwelling predatory bacteria known for their antimicrobial potential. Many pathogenic bacteria form biofilms to protect themselves from antimicrobial agents and the immune system. This study...
2.
Radford E, Whitworth D
Adv Microb Physiol
. 2024 Jul;
85:1-55.
PMID: 39059819
Myxobacteria (phylum Myxococcota) are abundant and virtually ubiquitous microbial predators. Facultatively multicellular organisms, they are able to form multicellular fruiting bodies and swarm across surfaces, cooperatively hunting for prey. Myxobacterial...
3.
Li Z, Zhu H, Whitworth D, Stevens D
Front Microbiol
. 2024 Jul;
15:1450345.
PMID: 39035443
No abstract available.
4.
Swetha R, Arakal B, Rajendran S, Sekar K, Whitworth D, Ramaiah S, et al.
Database (Oxford)
. 2024 Jul;
2024.
PMID: 38958433
Myxobacteria are predatory bacteria with antimicrobial activity, utilizing complex mechanisms to kill their prey and assimilate their macromolecules. Having large genomes encoding hundreds of secondary metabolites, hydrolytic enzymes and antimicrobial...
5.
Arakal B, Rowlands R, McCarthy M, Whitworth D, Maddocks S, James P, et al.
J Appl Microbiol
. 2024 Apr;
135(5).
PMID: 38649930
Aim: Corallococcus species are diverse in the natural environment with 10 new Corallococcus species having been characterized in just the last 5 years. As well as being an abundant myxobacterial...
6.
Swain M, Radford E, Akanyeti A, Hallwood J, Whitworth D
Mol Omics
. 2023 Dec;
20(2):138-145.
PMID: 38098456
The outer membrane vesicles (OMVs) secreted by some Gram-negative bacteria contain RNA cargo, which can be introduced into target cells, affecting their cellular processes. To test whether the antimicrobial OMVs...
7.
Radford E, Whitworth D, Allison G
Access Microbiol
. 2023 Nov;
5(10).
PMID: 37970077
Myxobacteria produce a variety of bioactive secondary metabolites, and with a wealth of under-researched species they hold vast potential for undiscovered compounds. With the ever-increasing need for new antibiotics, the...
8.
Whitworth D, Perez J, Mitchell R, Pande S
Front Microbiol
. 2023 Aug;
14:1256252.
PMID: 37577415
No abstract available.
9.
Zwarycz A, Page T, Nikolova G, Radford E, Whitworth D
Microorganisms
. 2023 Apr;
11(4).
PMID: 37110297
Predatory outer membrane vesicles (OMVs) secreted by myxobacteria fuse readily with the outer membranes of Gram-negative bacteria, introducing toxic cargo into their prey. Here we used a strain of the...
10.
Zwarycz A, Whitworth D
Microorganisms
. 2023 Feb;
11(2).
PMID: 36838363
Myxobacteria prey upon a broad range of microorganisms. Lawn assays are commonly used to quantify myxobacterial predation-myxobacterial suspensions are spotted onto prey lawns, and monitored via spot expansion. The diversity...