David E Theobald
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Explore the profile of David E Theobald including associated specialties, affiliations and a list of published articles.
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16
Citations
1159
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Recent Articles
1.
Alsio J, Lehmann O, McKenzie C, Theobald D, Searle L, Xia J, et al.
Cereb Cortex
. 2020 Oct;
31(2):1090-1105.
PMID: 33043981
Cross-species studies have identified an evolutionarily conserved role for serotonin in flexible behavior including reversal learning. The aim of the current study was to investigate the contribution of serotonin within...
2.
Merlo E, Milton A, Goozee Z, Theobald D, Everitt B
J Neurosci
. 2014 Feb;
34(7):2422-31.
PMID: 24523532
Memory persistence is critically influenced by retrieval. In rats, a single presentation of a conditioned fear stimulus induces memory reconsolidation and fear memory persistence, while repeated fear cue presentations result...
3.
Eagle D, Noschang C, dAngelo L, Noble C, Day J, Dongelmans M, et al.
Behav Brain Res
. 2014 Jan;
264:207-29.
PMID: 24406720
Excessive checking is a common, debilitating symptom of obsessive-compulsive disorder (OCD). In an established rodent model of OCD checking behaviour, quinpirole (dopamine D2/3-receptor agonist) increased checking in open-field tests, indicating...
4.
Spieth S, Schumacher A, Trenkle F, Brett O, Seidl K, Herwik S, et al.
Biomed Tech (Berl)
. 2013 Oct;
59(4):291-303.
PMID: 24101367
Intracortical microprobes allow the precise monitoring of electrical and chemical signaling and are widely used in neuroscience. Microelectromechanical system (MEMS) technologies have greatly enhanced the integration of multifunctional probes by...
5.
Spieth S, Schumacher A, Holtzman T, Rich P, Theobald D, Dalley J, et al.
Biomed Microdevices
. 2012 May;
14(5):799-809.
PMID: 22622711
Microinfusions of drugs directly into the central nervous system of awake animals represent a widely used means of unravelling brain functions related to behaviour. However, current approaches generally use tethered...
6.
Fernando A, Economidou D, Theobald D, Zou M, Newman A, Spoelder M, et al.
Psychopharmacology (Berl)
. 2011 Jul;
219(2):341-52.
PMID: 21761147
Rationale: Impulsivity is associated with a number of psychiatric disorders, most notably attention deficit/hyperactivity disorder (ADHD). Drugs that augment catecholamine function (e.g. methylphenidate and the selective noradrenaline reuptake inhibitor atomoxetine)...
7.
Bari A, Mar A, Theobald D, Elands S, Oganya K, Eagle D, et al.
J Neurosci
. 2011 Jun;
31(25):9254-63.
PMID: 21697375
Defining the neural and neurochemical substrates of response inhibition is of crucial importance for the study and treatment of pathologies characterized by impulsivity such as attention-deficit/hyperactivity disorder and addiction. The...
8.
Eagle D, Wong J, Allan M, Mar A, Theobald D, Robbins T
J Neurosci
. 2011 May;
31(20):7349-56.
PMID: 21593319
Dopamine and dopamine-receptor function are often implicated in behavioral inhibition, and deficiencies within behavioral inhibition processes linked to attention deficit/hyperactivity disorder (ADHD), schizophrenia, obsessive-compulsive disorder, and drug addiction. In the...
9.
Mar A, Walker A, Theobald D, Eagle D, Robbins T
J Neurosci
. 2011 Apr;
31(17):6398-404.
PMID: 21525280
The orbitofrontal cortex (OFC) is implicated in a variety of adaptive decision-making processes. Human studies suggest that there is a functional dissociation between medial and lateral OFC (mOFC and lOFC,...
10.
Bari A, Theobald D, Caprioli D, Mar A, Aidoo-Micah A, Dalley J, et al.
Neuropsychopharmacology
. 2010 Jan;
35(6):1290-301.
PMID: 20107431
Depressed patients show cognitive deficits that may depend on an abnormal reaction to positive and negative feedback. The precise neurochemical mechanisms responsible for such cognitive abnormalities have not yet been...