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David Durantel

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Articles 127
Citations 3699
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Recent Articles
1.
Dumolard L, Gerster T, Chuffart F, Decaens T, Hilleret M, Larrat S, et al.
Hepatol Commun . 2025 Jan; 9(2). PMID: 39878655
Background: Hepatitis B is a liver infection caused by HBV. Infected individuals who fail to control the viral infection develop chronic hepatitis B and are at risk of developing life-threatening...
2.
Welch S, Bilello J, Carter K, Delang L, Dirr L, Durantel D, et al.
Antiviral Res . 2024 Nov; 232:106037. PMID: 39542140
The 37th International Conference on Antiviral Research (ICAR) was held in Gold Coast, Australia, May 20-24, 2024. ICAR 2024 featured over 75 presentations along with two poster sessions and special...
3.
Pastor F, Charles E, Di Vona C, Chapelle M, Rivoire M, Passot G, et al.
PLoS One . 2024 Oct; 19(10):e0311655. PMID: 39405283
The genome of Hepatitis B virus (HBV) persists in infected hepatocytes as a nuclear episome (cccDNA) that is responsible for the transcription of viral genes and viral rebound, following antiviral...
4.
Pastor F, Charles E, Belmudes L, Chabrolles H, Cescato M, Rivoire M, et al.
Front Microbiol . 2024 Jun; 15:1415449. PMID: 38841065
Phosphorylation is a major post-translation modification (PTM) of proteins which is finely tuned by the activity of several hundred kinases and phosphatases. It controls most if not all cellular pathways...
5.
Shkreta L, Toutant J, Delannoy A, Durantel D, Salvetti A, Ehresmann S, et al.
Oncotarget . 2024 May; 15:313-325. PMID: 38753413
The diheteroarylamide-based compound 1C8 and the aminothiazole carboxamide-related compound GPS167 inhibit the CLK kinases, and affect the proliferation of a broad range of cancer cell lines. A chemogenomic screen previously...
6.
Spengler J, Carter K, Delang L, Durantel D, Gowen B, Herrero L, et al.
Antiviral Res . 2023 Jul; 217:105678. PMID: 37494979
The 36th International Conference on Antiviral Research (ICAR), sponsored by the International Society for Antiviral Research (ISAR), was held March 13-17, 2023, in Lyon, France, and concurrently through an interactive...
7.
Legrand A, Lucifora J, Lacombe B, Menard C, Michelet M, Foca A, et al.
Hepatol Commun . 2023 Apr; 7(5). PMID: 37058078
Background And Aims: HDV, a satellite of HBV, is responsible for the most severe form of human viral hepatitis, for which curative therapy is still awaited. Both HBV and HDV...
8.
Schrader J, Burkard T, Bruggemann Y, Gomer A, Meister T, Fu R, et al.
Hepatology . 2023 Feb; 77(6):2104-2117. PMID: 36745934
Background And Aims: Being the most common cause of acute viral hepatitis with >20 million cases per year and 70,000 deaths annually, HEV presents a long-neglected and underinvestigated health burden....
9.
Lecoq L, Brigandat L, Huber R, Fogeron M, Wang S, Dujardin M, et al.
Nat Commun . 2023 Jan; 14(1):471. PMID: 36709212
Hepatitis B virus (HBV) capsid assembly modulators (CAMs) represent a recent class of anti-HBV antivirals. CAMs disturb proper nucleocapsid assembly, by inducing formation of either aberrant assemblies (CAM-A) or of...
10.
Lucifora J, Alfaiate D, Pons C, Michelet M, Ramirez R, Fusil F, et al.
J Hepatol . 2023 Jan; 78(5):958-970. PMID: 36702177
Background & Aims: Chronic coinfection with HBV and HDV leads to the most aggressive form of chronic viral hepatitis. Herein, we aimed to elucidate the molecular mechanisms underlying the widely...