David C Ward
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Explore the profile of David C Ward including associated specialties, affiliations and a list of published articles.
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38
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1549
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Recent Articles
1.
Robinett H, Leon Guerrero R, Peterson J, Ward D, Palafox N, Vogel C
Hawaii J Med Public Health
. 2019 Jun;
78(6):205-207.
PMID: 31205817
This manuscript describes the efforts in research, education, and outreach of a unique partnership between the University of Hawai'i Cancer Center and the University of Guam in addressing cancer health...
2.
Leung E, Luo L, Li Y, Liu Z, Li L, Shi D, et al.
Int J Cancer
. 2019 Feb;
145(5):1334-1345.
PMID: 30786019
Oncogenic KRAS is considered a promising target for anti-cancer therapy. However, direct pharmacological strategies targeting KRAS-driven cancers remained unavailable. The prenyl-binding protein PDEδ, a transporter of KRAS, has been identified...
3.
Leung E, Luo L, Liu Z, Wong V, Lu L, Xie Y, et al.
Cell Death Dis
. 2018 Feb;
9(2):216.
PMID: 29440631
Deltarasin is a recently identified small molecule that can inhibit KRAS-PDEδ interactions by binding to a hydrophobic pocket on PDEδ, resulting in the impairment of cell growth, KRAS activity, and...
4.
Torres A, Sweeten T, Johnson R, Odell D, Westover J, Bray-Ward P, et al.
Front Neurosci
. 2016 Nov;
10:463.
PMID: 27812316
The "common variant-common disease" hypothesis was proposed to explain diseases with strong inheritance. This model suggests that a genetic disease is the result of the combination of several common genetic...
5.
Simon L, Ward D
Curr Sports Med Rep
. 2014 May;
13(3):163-8.
PMID: 24819007
The participation in sports for physically challenged athletes continues to expand in multiple domains from recreational, novice, and competitive to elite competitions such as the Paralympics. Physically challenged athletes have...
6.
Torres A, Westover J, Gibbons C, Johnson R, Ward D
Brain Behav Immun
. 2012 Aug;
26(7):1122-7.
PMID: 22884899
Killer-cell immunoglobulin-like receptor (KIR) proteins are expressed on natural killer (NK) cells and appear important in innate and adaptive immunity. There are about 14 KIR genes on chromosome 19q13.4, composed...
7.
Xu D, O T, Shartava A, Fowles T, Yang J, Fink L, et al.
J Hematol Oncol
. 2011 Dec;
4:54.
PMID: 22192404
Background: Infantile hemangiomas (IH) are the most common benign tumors of infancy. The typical clinical course consists of rapid growth during the first year of life, followed by natural and...
8.
Gonzales J, Fink L, Goodman Jr O, Symanowski J, Vogelzang N, Ward D
Clin Genitourin Cancer
. 2011 Jul;
9(1):39-45.
PMID: 21723797
Our aim was to determine the utility of circulating micro RNA miR-141 as a potential biomarker of therapeutic response in prostate cancer (CaP) patients. We compared the values of miR-141...
9.
Circulating tumor cells as a predictive biomarker in patients with hormone-sensitive prostate cancer
Goodman Jr O, Symanowski J, Loudyi A, Fink L, Ward D, Vogelzang N
Clin Genitourin Cancer
. 2011 Jun;
9(1):31-8.
PMID: 21705286
Unlabelled: Little information exists regarding the utility circulating tumor cell (CTC) enumeration in hormone sensitive prostate cancer. We enumerated CTC in 33 consecutive patients undergoing androgren deprivation therapy (ADT) at...
10.
Alipio Z, Jones N, Liao W, Yang J, Kulkarni S, Kumar K, et al.
Differentiation
. 2011 May;
82(2):89-98.
PMID: 21596473
Induced pluripotent stem (iPS) cells are derived from reprogrammed somatic cells and are similar to embryonic stem (ES) cells in morphology, gene/protein expression, and pluripotency. In this study, we explored...