David Burstein
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Explore the profile of David Burstein including associated specialties, affiliations and a list of published articles.
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65
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3369
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Recent Articles
1.
Rannon E, Shaashua S, Burstein D
Microbiome
. 2025 Mar;
13(1):67.
PMID: 40055840
Background: Antibiotics are essential for medical procedures, food security, and public health. However, ill-advised usage leads to increased pathogen resistance to antimicrobial substances, posing a threat of fatal infections and...
2.
Burstein D, Tomasi S, Venkatesh S, Rizk M, Roussos P, Voloudakis G
medRxiv
. 2025 Feb;
PMID: 39974071
Importance: Researchers commonly use counts of diagnostic codes from EHR-linked biobanks to infer phenotypic status. However, these approaches overlook temporal changes in EHR data, such as the discontinuation or "dropout"...
3.
N M P, Fullard J, Clarence T, Mathur D, Casey C, Hennigan E, et al.
Sci Data
. 2024 Nov;
11(1):1274.
PMID: 39580497
Parkinson's Disease (PD) is a debilitating neurodegenerative disorder, characterized by motor and cognitive impairments, that affects >1% of the population over the age of 60. The pathogenesis of PD is...
4.
Samuel B, Mittelman K, Croitoru S, Ben Haim M, Burstein D
Nature
. 2024 Oct;
635(8037):186-192.
PMID: 39385022
Plasmids are major drivers of gene mobilization by means of horizontal gene transfer and play a key role in spreading antimicrobial resistance among pathogens. Despite various bacterial defence mechanisms such...
5.
Bigdeli T, Chatzinakos C, Bendl J, Barr P, Venkatesh S, Gorman B, et al.
medRxiv
. 2024 Sep;
PMID: 39252912
Large-scale genome-wide association studies of schizophrenia have uncovered hundreds of associated loci but with extremely limited representation of African diaspora populations. We surveyed electronic health records of 200,000 individuals of...
6.
Kang J, Castro V, Ripperger M, Venkatesh S, Burstein D, Linner R, et al.
Am J Psychiatry
. 2024 May;
181(7):608-619.
PMID: 38745458
Objective: Treatment-resistant depression (TRD) occurs in roughly one-third of all individuals with major depressive disorder (MDD). Although research has suggested a significant common variant genetic component of liability to TRD,...
7.
Miller D, Arias O, Burstein D
Bioinformatics
. 2024 Jan;
40(2).
PMID: 38291951
Summary: GeNLP is a web application that enables exploring microbial gene "semantics" and predictions of uncharacterized gene families based on their genomic context. It utilizes a pre-trained language model to...
8.
Harari S, Miller D, Fleishon S, Burstein D, Stern A
Nat Commun
. 2024 Jan;
15(1):648.
PMID: 38245511
The evolution of SARS-Coronavirus-2 (SARS-CoV-2) has been characterized by the periodic emergence of highly divergent variants. One leading hypothesis suggests these variants may have emerged during chronic infections of immunocompromised...
9.
Hershko Y, Rannon E, Adler A, Burstein D, Barkan D
Int J Antimicrob Agents
. 2024 Jan;
63(2):107089.
PMID: 38218322
Objectives: Aminoglycoside resistance in bacteria is typically conferred by specific drug-modifying enzymes. Infrequently, such resistance is achieved through 16S ribosomal RNA methyltransferases, such as NpmA and KamB encoded by Escherichia...
10.
Burstein D, Griffen T, Therrien K, Bendl J, Venkatesh S, Dong P, et al.
Nat Genet
. 2023 Aug;
55(9):1462-1470.
PMID: 37550530
Binge eating disorder (BED) is the most common eating disorder, yet its genetic architecture remains largely unknown. Studying BED is challenging because it is often comorbid with obesity, a common...