David Boone
Overview
Explore the profile of David Boone including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
988
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Recent Articles
1.
Chawla P, Sharma I, Gau D, Eder I, Chen F, Yu V, et al.
Mol Biol Cell
. 2024 Dec;
36(1):ar8.
PMID: 39630611
Bone is a frequent site for breast cancer metastasis. The vast majority of breast cancer-associated metastasis is osteolytic in nature, and RANKL (receptor activator for nuclear factor κB)-induced differentiation of...
2.
Eder I, Yu V, Antonello J, Chen F, Gau D, Chawla P, et al.
Mol Biol Cell
. 2024 Aug;
35(10):ar133.
PMID: 39196658
Dysregulated actin cytoskeleton gives rise to aberrant cell motility and metastatic spread of tumor cells. This study evaluates the effect of overexpression of wild-type versus functional mutants of MRTF-A on...
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Eder I, Yu V, Antonello J, Chen F, Gau D, Chawla P, et al.
bioRxiv
. 2024 Jan;
PMID: 38187641
Significance: Actin cytoskeletal dysregulation gives rise to metastatic dissemination of cancer cells. This study mechanistically investigates the impact of specific functional disruption of MRTF (a transcriptional co-factor of SRF) on...
6.
Chawla P, Sharma I, Gau D, Eder I, Chen F, Yu V, et al.
bioRxiv
. 2023 Dec;
PMID: 38106226
Significance Statement: MRTF, a transcriptional coactivator of SRF, is known to promote breast cancer progression through its tumor-cell-intrinsic function. Whether and how MRTF activity in tumor cells modulates other types...
7.
Allen-Gondringer A, Gau D, Varghese C, Boone D, Stolz D, Larregina A, et al.
PNAS Nexus
. 2023 Oct;
2(10):pgad305.
PMID: 37781098
Actin-binding protein Profilin1 is an important regulator of actin cytoskeletal dynamics in cells and critical for embryonic development in higher eukaryotes. The objective of the present study was to examine...
8.
Gau D, Daoud A, Allen A, Joy M, Sagan A, Lee S, et al.
J Biol Chem
. 2023 Jul;
299(8):105044.
PMID: 37451478
Overexpression of actin-binding protein profilin-1 (Pfn1) correlates with advanced disease features and adverse clinical outcome of patients with clear cell renal carcinoma, the most prevalent form of renal cancer. We...
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