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David Astapenko

Explore the profile of David Astapenko including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 123
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Recent Articles
1.
Hana L, Tlapakova K, Cizkova D, Ticha A, Lehmann C, Cerny V, et al.
Clin Hemorheol Microcirc . 2025 Feb; :13860291241306568. PMID: 39973440
Background: The ischemia-reperfusion injury (IRI) is unavoidable in vascular surgery. Damage to the microcirculation and endothelial glycocalyx might set up a shock with loss of circulatory coherence and organ failure....
2.
Astapenko D, Gorskaja D, Zrzavecky M, Kawashima H, Ssali E, Navratil P, et al.
Clin Hemorheol Microcirc . 2025 Feb; :13860291241305514. PMID: 39973431
Background: Sulodexide is a glycosaminoglycan-based drug prescribed to patients with angiopathy. We performed a pilot study to investigate whether sulodexide positively modulates the endothelial glycocalyx (EG) layer and the microcirculation...
3.
Kalina M, Vargova P, Bubenikova A, Skulec R, Cerny V, Astapenko D
Ultrasound J . 2025 Jan; 17(1):5. PMID: 39821817
Background: The cannulation of the internal jugular vein (IJV) is a frequent procedure in critically ill patients. According to the guidelines, real-time ultrasound navigation is recommended. Traditional techniques pose several...
4.
Navratil P, Sahi S, Hruba P, Ticha A, Timkova K, Viklicky O, et al.
Transplant Proc . 2025 Jan; 57(2):187-193. PMID: 39809657
Background: The process of kidney transplantation remains the optimal treatment for end-stage renal disease, offering improved quality of life and increased survival rates compared to long-term dialysis. However, despite advances...
5.
Hahn R, Tlapakova K, Koudelova H, Knoblochova V, Rehak D, Cerny V, et al.
Microvasc Res . 2024 Dec; 158:104781. PMID: 39740739
Background: Excess fluid in the interstitium can adversely affect the microcirculation. We studied how gradual dilution of the blood plasma by crystalloid fluid influences microcirculatory variables and capillary filtration in...
6.
Merkl T, Astapenko D, Stichhauer R, Safus A, Dusek T, Kotek J, et al.
Clin Respir J . 2024 May; 18(5):e13776. PMID: 38778673
This systematic review aimed to summarize the available data on the treatment of pulmonary contusions with exogenous surfactants, determine whether this treatment benefits patients with severe pulmonary contusions, and evaluate...
7.
Astapenko D, Vajrychova M, Fabrik I, Kupcik R, Pimkova K, Tambor V, et al.
Heliyon . 2024 Mar; 10(6):e27638. PMID: 38509933
Anesthesia is regarded as an important milestone in medicine. However, the negative effect on memory and learning has been observed. In addition, the impact of anesthetics on postoperative cognitive functions...
8.
Astapenko D, Zrzavecky M, Gorskaja D, Hyspler R, Ticha A, Radochova V, et al.
Clin Hemorheol Microcirc . 2023 Dec; 86(4):509-517. PMID: 38073383
Background: Endothelial glycocalyx (EG) plays a crucial role in maintaining the plasma proteins within the intravascular space. Objective: We studied whether exogenous albumin protects the EG in an experimental model...
9.
Navratil P, Sahi S, Spacek J, Pacovsky J, Lesko M, Gunka I, et al.
Exp Clin Transplant . 2023 Oct; 21(9):712-716. PMID: 37885285
Objectives: We evaluated the feasibility, safety, and long-term outcomes of pyelovesicostomy as an alternative surgical treatment for complex ureteral lesions after kidney transplant. Materials And Methods: A single-center, retrospective, observational...
10.
Astapenko D, Hyspler R, Ticha A, Tomasova A, Navratil P, Zrzavecky M, et al.
Clin Hemorheol Microcirc . 2023 Sep; 85(2):135-146. PMID: 37694356
Background: Hydrogen is a potent antioxidant agent that can easily be administered by inhalation. The aim of the study was to evaluate whether hydrogen protects the endothelial glycocalyx layer after...