David Astapenko
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Explore the profile of David Astapenko including associated specialties, affiliations and a list of published articles.
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24
Citations
123
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Recent Articles
11.
Sirovy M, Krupova M, Hyspler R, Ticha A, Kolackova M, Andrys C, et al.
Asian J Surg
. 2022 Jun;
46(1):465-471.
PMID: 35688763
Introduction: Adhesions are the most common cause of long-term morbidity after abdominal surgery and most often cause various forms of intestinal passage disorders ranging from partial obstruction to complete, life-threatening...
12.
Astapenko D, Tomasova A, Ticha A, Hyspler R, Chua H, Manzoor M, et al.
Clin Hemorheol Microcirc
. 2022 Mar;
81(3):205-219.
PMID: 35342082
Background: Coronavirus disease (COVID-19) associated endotheliopathy and microvascular dysfunction are of concern. Objective: The objective of the present single-center observational pilot study was to compare endothelial glycocalyx (EG) damage and...
13.
Parizkova R, Martinkova J, Havel E, Safranek P, Kaska M, Astapenko D, et al.
Crit Care
. 2021 Jul;
25(1):251.
PMID: 34274013
Background: Meropenem dosing for septic critically patients is difficult due to pathophysiological changes associated with sepsis as well as supportive symptomatic therapies. A prospective single-center study assessed whether fluid retention...
14.
Astapenko D, Ticha A, Hyspler R, Tomasova A, Navratil P, Maly O, et al.
Clin Hemorheol Microcirc
. 2021 Apr;
78(3):325-338.
PMID: 33843666
Background: The endothelial glycocalyx (EG) plays a vital role in the physiology and pathophysiology of human microcirculation. Having relevant EG damage model would be important tool for testing new interventions...
15.
Astapenko D, Navratil P, Pouska J, Cerny V
Perioper Med (Lond)
. 2020 Dec;
9(1):40.
PMID: 33298166
Background: This systematic review discusses a clinical physiology aspect of chloride in fluid therapy. Crystalloid solutions are one of the most widely used remedies. While generally used in medicine for...
16.
Maly O, Zajak J, Hyspler R, Turek Z, Astapenko D, Jun D, et al.
Ann Transl Med
. 2020 Feb;
7(23):774.
PMID: 32042790
Background: Liver resection is a surgical procedure associated with a high risk of hepatic failure that can be fatal. One of the key mechanisms involves ischemia-reperfusion damage. Building on the...
17.
Kucharova M, Astapenko D, Zubanova V, Koscakova M, Stetina R, Zadak Z, et al.
Int J Mol Sci
. 2019 Dec;
21(1).
PMID: 31877659
The human organism is exposed daily to many endogenous and exogenous substances that are the source of oxidative damage. Oxidative damage is one of the most frequent types of cell...
18.
Astapenko D, Benes J, Pouska J, Lehmann C, Islam S, Cerny V
BMC Anesthesiol
. 2019 Dec;
19(1):238.
PMID: 31862008
The endothelial glycocalyx (EG) is the thin sugar-based lining on the apical surface of endothelial cells. It has been linked to the physiological functioning of the microcirculation and has been...
19.
Astapenko D, Ticha A, Tomasova A, Hyspler R, Zadak Z, Lehmann C, et al.
Clin Hemorheol Microcirc
. 2019 Nov;
75(3):257-265.
PMID: 31683466
Background: Endothelial glycocalyx (EG) is a carbohydrate-rich gel-like mesh covering the apical surface of endothelial cells. It has been linked to the microvascular pathophysiology and tissue metabolism. However, little is...
20.
Astapenko D, Turek Z, Dostal P, Hyspler R, Ticha A, Kaska M, et al.
Clin Hemorheol Microcirc
. 2019 Jul;
73(2):329-339.
PMID: 31306112
Background: Endothelial glycocalyx (EG) is a carbohydrate-rich vascular lining of the apical surface of endothelial cells. It has been proved to have an essential role in vascular homeostasis. Lipid emulsions...