David Ackerman
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Explore the profile of David Ackerman including associated specialties, affiliations and a list of published articles.
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10
Citations
738
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Recent Articles
1.
Renganathan B, Moore A, Yeo W, Petruncio A, Ackerman D, Weigel A, et al.
J Cell Biol
. 2025 Mar;
224(4).
PMID: 40062969
Vimentin intermediate filaments (VIFs) form complex, tightly packed networks; due to this density, traditional imaging approaches cannot discern single-filament behavior. To address this, we developed and validated a sparse vimentin-SunTag...
2.
Renganathan B, Moore A, Yeo W, Petruncio A, Ackerman D, Wiegel A, et al.
bioRxiv
. 2024 Jun;
PMID: 38915582
Single-particle tracking demonstrates that individual filaments in bundles of vimentin intermediate filaments are transported in the cytoplasm by motor proteins along microtubules. Furthermore, using 3D FIB-SEM the authors showed that...
3.
Bharathan N, Giang W, Hoffman C, Aaron J, Khuon S, Chew T, et al.
Nat Cell Biol
. 2024 Feb;
26(4):660.
PMID: 38347183
No abstract available.
4.
Knox C, Wilson M, Klinger C, Franklin M, Oler E, Wilson A, et al.
Nucleic Acids Res
. 2023 Nov;
52(D1):D1265-D1275.
PMID: 37953279
First released in 2006, DrugBank (https://go.drugbank.com) has grown to become the 'gold standard' knowledge resource for drug, drug-target and related pharmaceutical information. DrugBank is widely used across many diverse biomedical...
5.
Bharathan N, Giang W, Hoffman C, Aaron J, Khuon S, Chew T, et al.
Nat Cell Biol
. 2023 Jun;
25(6):823-835.
PMID: 37291267
The endoplasmic reticulum (ER) forms a dynamic network that contacts other cellular membranes to regulate stress responses, calcium signalling and lipid transfer. Here, using high-resolution volume electron microscopy, we find...
6.
Alam S, Eom T, Steinberg J, Ackerman D, Schmitt J, Akers W, et al.
Front Bioinform
. 2022 Oct;
2:865443.
PMID: 36304320
Segmentation of mouse brain magnetic resonance images (MRI) based on anatomical and/or functional features is an important step towards morphogenetic brain structure characterization of murine models in neurobiological studies. State-of-the-art...
7.
Bulumulla C, Krasley A, Cristofori-Armstrong B, Valinsky W, Walpita D, Ackerman D, et al.
Elife
. 2022 Jul;
11.
PMID: 35786443
Chemical neurotransmission constitutes one of the fundamental modalities of communication between neurons. Monitoring release of these chemicals has traditionally been difficult to carry out at spatial and temporal scales relevant...
8.
Ritter A, Shtengel G, Xu C, Weigel A, Hoffman D, Freeman M, et al.
Science
. 2022 Apr;
376(6591):377-382.
PMID: 35446649
Cytotoxic T lymphocytes (CTLs) and natural killer cells kill virus-infected and tumor cells through the polarized release of perforin and granzymes. Perforin is a pore-forming toxin that creates a lesion...
9.
Heinrich L, Bennett D, Ackerman D, Park W, Bogovic J, Eckstein N, et al.
Nature
. 2021 Oct;
599(7883):141-146.
PMID: 34616042
Cells contain hundreds of organelles and macromolecular assemblies. Obtaining a complete understanding of their intricate organization requires the nanometre-level, three-dimensional reconstruction of whole cells, which is only feasible with robust...
10.
Scheffer L, Xu C, Januszewski M, Lu Z, Takemura S, Hayworth K, et al.
Elife
. 2020 Sep;
9.
PMID: 32880371
The neural circuits responsible for animal behavior remain largely unknown. We summarize new methods and present the circuitry of a large fraction of the brain of the fruit fly ....